[HTML][HTML] Brugada syndrome: A comprehensive review of pathophysiological mechanisms and risk stratification strategies

KHC Li, S Lee, C Yin, T Liu, T Ngarmukos, G Conte… - IJC Heart & …, 2020 - Elsevier
Brugada syndrome (BrS) is an inherited ion channel channelopathy predisposing to
ventricular arrhythmias and sudden cardiac death. Originally believed to be predominantly …

[HTML][HTML] Comparing the performance of published risk scores in Brugada syndrome: a multi-center cohort study

S Lee, J Zhou, CT Chung, ROY Lee, G Bazoukis… - Current Problems in …, 2022 - Elsevier
Abstract The management of Brugada Syndrome (BrS) patients at intermediate risk of
arrhythmic events remains controversial. The present study evaluated the predictive …

Territory-wide cohort study of Brugada syndrome in Hong Kong: predictors of long-term outcomes using random survival forests and non-negative matrix factorisation

S Lee, J Zhou, KHC Li, KSK Leung, I Lakhani, T Liu… - Open …, 2021 - openheart.bmj.com
Objectives Brugada syndrome (BrS) is an ion channelopathy that predisposes affected
patients to spontaneous ventricular tachycardia/fibrillation (VT/VF) and sudden cardiac …

Paediatric/young versus adult patients with long QT syndrome

S Lee, J Zhou, K Jeevaratnam, WT Wong… - Open …, 2021 - openheart.bmj.com
Introduction Long QT syndrome (LQTS) is a less prevalent cardiac ion channelopathy than
Brugada syndrome in Asia. The present study compared the outcomes between …

Incorporating latent variables using nonnegative matrix factorization improves risk stratification in Brugada syndrome

G Tse, J Zhou, S Lee, T Liu, G Bazoukis… - Journal of the …, 2020 - Am Heart Assoc
Background A combination of clinical and electrocardiographic risk factors is used for risk
stratification in Brugada syndrome. In this study, we tested the hypothesis that the …

Predictive risk models for forecasting arrhythmic outcomes in Brugada syndrome: A focused review

CT Chung, G Bazoukis, D Radford… - Journal of …, 2022 - Elsevier
Brugada syndrome (BrS) is a rare disorder characterized by coved or saddle-shaped ST-
segment elevation in the right precordial leads on the electrocardiogram. Risk stratification …

Automated electrocardiogram analysis identifies novel predictors of ventricular arrhythmias in Brugada syndrome

G Tse, S Lee, A Li, D Chang, G Li, J Zhou… - Frontiers in …, 2021 - frontiersin.org
Background: Patients suffering from Brugada syndrome (BrS) are at an increased risk of life-
threatening ventricular arrhythmias. Whilst electrocardiographic (ECG) variables have been …

Modeling genetic cardiac channelopathies using induced pluripotent stem cells–Status quo from an electrophysiological perspective

MVK Kamga, M Reppel, J Hescheler… - Biochemical …, 2021 - Elsevier
Abstract Long QT syndrome (LQTS), Brugada syndrome (BrS), and catecholaminergic
polymorphic ventricular tachycardia (CPVT) are genetic diseases of the heart caused by …

Twelve-lead ECG, Holter monitoring parameters, and genetic testing in Brugada syndrome: insights from analysis of multigenerational family with a history of sudden …

PT Matusik, P Bijak, M Kaźnica-Wiatr… - Journal of Clinical …, 2023 - mdpi.com
Brugada syndrome (BrS) is an arrhythmogenic disorder increasing the risk of syncopal
episodes and sudden cardiac death. BrS usually runs through families with reduced …

Wide QRS complex and the risk of major arrhythmic events in Brugada syndrome patients: A systematic review and meta‐analysis

P Rattanawong, J Kewcharoen… - Journal of …, 2020 - Wiley Online Library
Abstract Background Brugada syndrome (BrS) is an inherited arrhythmic disease associated
with an increased risk of major arrhythmic events (MAE). Previous studies reported that a …