Abstract The RNA World Hypothesis suggests that prebiotic life revolved around RNA
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …

Over the past decade, it has become clear that mammalian genomes encode thousands of
long non-coding RNAs (lncRNAs), many of which are now implicated in diverse biological …

Recent research has demonstrated that the non-coding genome plays a key role in genetic
programming and gene regulation during development as well as in health and …

Understanding the complex and specific roles played by non-coding RNAs (ncRNAs), which
comprise the bulk of the genome, is important for understanding virtually every hallmark of …

Innate immunity provides the initial defence against infection and it is now clear that long
non-coding RNAs (lncRNAs) are important regulators of this response. Following activation …

Long noncoding RNAs (lncRNAs) are non-protein-coding RNA transcripts that exert a key
role in many cellular processes and have potential toward addressing disease etiology …

Long noncoding RNAs (lncRNAs) are the largest groups of ribonucleic acids, but, despite
the increasing amount of literature data, the least understood. Given the involvement of …

RNA can directly bind to purine-rich DNA via Hoogsteen base pairing, forming a DNA: RNA
triple helical structure that anchors the RNA to specific sequences and allows guiding of …

A significant amount of RNA is present in the nucleus of mammalian cells but only a small
proportion of it is destined for the cytoplasm and subsequent translation, leaving much RNA …

Lung tumours are widespread pathological conditions that attract much attention due to their
high incidence of death. The immune system contributes to the progression of these …