TE Daniels, EM Olsen, AR Tyrka - Annual review of clinical …, 2020 - annualreviews.org
In seeking to understand mental health and disease, it is fundamental to identify the biological substrates that draw together the experiences and physiological processes that …
P Hautekiet, ND Saenen, DS Martens, M Debay… - BMC medicine, 2022 - Springer
Background Studies often evaluate mental health and well-being in association with individual health behaviours although evaluating multiple health behaviours that co-occur in …
Major depressive disorder (MDD) has been linked to mitochondrial defects, which could manifest in mitochondrial DNA (mtDNA) polymorphisms or mutations. Additionally, copy …
Mitochondria carry their own circular genome and disruption of the mitochondrial genome is associated with various aging-related diseases. Unlike the nuclear genome, mitochondrial …
S Ochi, B Roy, K Prall, RC Shelton, Y Dwivedi - Molecular psychiatry, 2023 - nature.com
Major depressive disorder (MDD) is highly prevalent in adolescents and is a major risk factor for suicidality. Recent evidence shows that accelerated cellular senescence/aging is …
Suicides have increased to over 48,000 deaths yearly in the United States. Major depressive disorder (MDD) is the most common diagnosis among suicides, and identifying those at the …
D Lindqvist, J Fernström, C Grudet, L Ljunggren… - Translational …, 2016 - nature.com
Preclinical data suggest that chronic stress may cause cellular damage and mitochondrial dysfunction, potentially leading to the release of mitochondrial DNA (mtDNA) into the …
CA Calarco, SM Keppetipola, G Kumar, AG Shipper… - Psychiatry …, 2024 - Elsevier
Major depressive disorder (MDD) and bipolar disorder (BD), are globally prevalent, contributing to significant disease burden and adverse health outcomes. These mood …
KK Ridout, SH Parade, HT Kao, S Magnan… - …, 2019 - Elsevier
Objective Childhood maltreatment is a major risk factor for the development of behavioral problems and poor physical and mental health. Accelerated cellular aging, through reduced …