IL-10 family cytokines IL-10 and IL-22: from basic science to clinical translation

W Ouyang, A O'Garra - Immunity, 2019 - cell.com
Cytokines are among the most important effector and messenger molecules in the immune
system. They profoundly participate in immune responses during infection and inflammation …

Cross-talk between antigen presenting cells and T cells impacts intestinal homeostasis, bacterial infections, and tumorigenesis

SJ Gaudino, P Kumar - Frontiers in immunology, 2019 - frontiersin.org
Innate immunity is maintained in part by antigen presenting cells (APCs) including dendritic
cells, macrophages, and B cells. APCs interact with T cells to link innate and adaptive …

[HTML][HTML] Type I interferons in infectious disease

F McNab, K Mayer-Barber, A Sher, A Wack… - Nature Reviews …, 2015 - nature.com
Type I interferons (IFNs) have diverse effects on innate and adaptive immune cells during
infection with viruses, bacteria, parasites and fungi, directly and/or indirectly through the …

[HTML][HTML] Type I interferon: friend or foe?

G Trinchieri - The Journal of experimental medicine, 2010 - ncbi.nlm.nih.gov
Although the role of type I interferon (IFN) in the protection against viral infections has been
known and studied for decades, its role in other immunologically relevant scenarios …

[HTML][HTML] Type I interferons in host defense

DB Stetson, R Medzhitov - Immunity, 2006 - cell.com
Type I interferons (IFNs) are a family of cytokines specialized to coordinate immunity to
viruses and other intracellular infections. In the past several years, many of the receptors …

Molecular mechanisms of inflammasome activation during microbial infections

P Broz, DM Monack - Immunological reviews, 2011 - Wiley Online Library
The innate immune system plays a crucial role in the rapid recognition and elimination of
invading microbes. Detection of microbes relies on germ‐line encoded pattern recognition …

Induction of IFN-αβ enables Listeria monocytogenes to suppress macrophage activation by IFN-γ

M Rayamajhi, J Humann, K Penheiter… - Journal of Experimental …, 2010 - rupress.org
Production of type I interferon (IFN; IFN-αβ) increases host susceptibility to Listeria
monocytogenes, whereas type II IFN (IFN-γ) activates macrophages to resist infection. We …

Alpha and beta type 1 interferon signaling: passage for diverse biologic outcomes

CT Ng, JL Mendoza, KC Garcia, MBA Oldstone - Cell, 2016 - cell.com
Alpha and Beta Type 1 Interferon Signaling: Passage for Diverse Biologic Outcomes: Cell Skip
to Main Content Advertisement Cell This journal offers authors two options (open access or …

Cell biology and immunology of Listeria monocytogenes infections: novel insights

F Stavru, C Archambaud, P Cossart - Immunological reviews, 2011 - Wiley Online Library
Listeria monocytogenes is an intracellular bacterium responsible for a disease characterized
by several clinical features, such as septicemia, brain infection, abortion, and perinatal …

[HTML][HTML] Innate and adaptive immune responses to Listeria monocytogenes: a short overview

LA Zenewicz, H Shen - Microbes and infection, 2007 - Elsevier
The Gram-positive facultative intracellular bacterium Listeria monocytogenes is a model
pathogen for elucidating important mechanisms of the immune response. Infection of mice …