Triterpenes as potentially cytotoxic compounds

M Chudzik, I Korzonek-Szlacheta, W Król - Molecules, 2015 - mdpi.com
Triterpenes are compounds of natural origin, which have numerously biological activities:
anti-cancer properties, anti-inflammatory, anti-oxidative, anti-viral, anti-bacterial and anti …

Triterpenoids

RA Hill, JD Connolly - Natural product reports, 2018 - pubs.rsc.org
Covering 2014. Previous review: Nat. Prod. Rep., 2017, 34, 90–122 This review covers the
isolation and structure determination of triterpenoids reported during 2014 including …

The antifeedant, insecticidal and insect growth inhibitory activities of triterpenoid saponins from Clematis aethusifolia Turcz against Plutella xylostella (L.)

X Tian, Y Li, N Hao, X Su, J Du, J Hu… - Pest Management …, 2021 - Wiley Online Library
BACKGROUND The diamondback moth, Plutella xylostella (L.)(Lepidoptera: Plutellidae), is
a global insect pest of crops, leading to a reduction of agricultural products in productivity …

Anticancer chemodiversity of Ranunculaceae medicinal plants: molecular mechanisms and functions

DC Hao, CN He, J Shen, PG Xiao - Current genomics, 2017 - ingentaconnect.com
The buttercup family, Ranunculaceae, comprising more than 2,200 species in at least 62
genera, mostly herbs, has long been used in folk medicine and worldwide ethnomedicine …

Cytotoxic triterpenoid saponins from Clematis tangutica

M Zhao, ZM Da-Wa, DL Guo, DM Fang, XZ Chen… - Phytochemistry, 2016 - Elsevier
Eight previously undescribed oleanane-type triterpenoid saponins, clematangoticosides AH,
together with eight known saponins, were isolated from the whole plants of Clematis …

Reduction of SCUBE3 by a new marine-derived asterosaponin leads to arrest of glioma cells in G1/S

PC Qiu, YY Lu, S Zhang, H Li, H Bao, YQ Ji, F Fang… - Oncogenesis, 2020 - nature.com
Many saponins are characterized as exhibiting a wide spectrum of antitumor activities at low
concentrations. Most of the previous studies that aimed to understand the mechanisms …

[HTML][HTML] Promotion of Ros-mediated Bax/Cyt-c apoptosis by polyphyllin II leads to suppress growth and aggression of glioma cells

G Cheng, YY Xue, F Fang, GQ Sun, YY Lu… - Translational Cancer …, 2021 - ncbi.nlm.nih.gov
Background: Gliomas remain among the most difficult cancers to treat, with a 5-year overall
survival no greater than 5%. Many saponins showed a wide spectrum of anti-cancer …

Ion mobility mass spectrometry of saponin ions

C Decroo, E Colson, V Lemaur… - Rapid …, 2019 - Wiley Online Library
Results: We demonstrate that ion mobility can contribute to the structural characterization of
saponins because different saponin ions present significantly distinct CCSs. Depending on …

New steroidal saponins from the rhizomes of Paris delavayi and their cytotoxicity

Y Liu, X Tian, D Hua, G Cheng, K Wang, L Zhang… - Fitoterapia, 2016 - Elsevier
Four new furostanol saponins, named padelaosides C–F (1–4), together with four known
spirostanol saponins 5–8 were isolated from the rhizomes of Paris delavayi Franchet. Their …

CN‐3 increases TMZ sensitivity and induces ROS‐dependent apoptosis and autophagy in TMZ‐resistance glioblastoma

YY Xue, YY Lu, GQ Sun, F Fang, YQ Ji… - … of Biochemical and …, 2022 - Wiley Online Library
Many glioma patients develop resistance to temozolomide (TMZ) treatment, resulting in
reduced efficacy and survival rates. TMZ‐resistant cell lines SHG44R and U87R, which …