Molecular pathology of endometrial carcinoma
X Matias‐Guiu, J Prat - Histopathology, 2013 - Wiley Online Library
This review paper discusses the main molecular alterations of endometrial carcinoma, the
most common cancer of the female genital tract. Two clinicopathological variants are …
most common cancer of the female genital tract. Two clinicopathological variants are …
The biological kinship of hypoxia with CSC and EMT and their relationship with deregulated expression of miRNAs and tumor aggressiveness
B Bao, AS Azmi, S Ali, A Ahmad, Y Li… - … et Biophysica Acta (BBA …, 2012 - Elsevier
Hypoxia is one of the fundamental biological phenomena that are intricately associated with
the development and aggressiveness of a variety of solid tumors. Hypoxia-inducible factors …
the development and aggressiveness of a variety of solid tumors. Hypoxia-inducible factors …
Endometrial carcinoma: molecular alterations involved in tumor development and progression
A Yeramian, G Moreno-Bueno, X Dolcet, L Catasus… - Oncogene, 2013 - nature.com
In the western world, endometrial carcinoma (EC) is the most common cancer of the female
genital tract. The annual incidence has been estimated at 10–20 per 100 000 women. Two …
genital tract. The annual incidence has been estimated at 10–20 per 100 000 women. Two …
Marine bioactives: Pharmacological properties and potential applications against inflammatory diseases
N D'Orazio, MA Gammone, E Gemello, M De Girolamo… - Marine drugs, 2012 - mdpi.com
Inflammation is a hot topic in medical research, because it plays a key role in inflammatory
diseases: rheumatoid arthritis (RA) and other forms of arthritis, diabetes, heart diseases …
diseases: rheumatoid arthritis (RA) and other forms of arthritis, diabetes, heart diseases …
Endometrial Cancer Cells Promote M2‐Like Macrophage Polarization by Delivering Exosomal miRNA‐21 under Hypoxia Condition
L Xiao, Y He, F Peng, J Yang… - Journal of Immunology …, 2020 - Wiley Online Library
Increasing evidence has demonstrated that hypoxia was an aggressive feature in
endometrial cancer (EC), which is significantly associated with the tumor grade, lymph node …
endometrial cancer (EC), which is significantly associated with the tumor grade, lymph node …
Immunological dimensions of neuroinflammation and microglial activation: exploring innovative immunomodulatory approaches to mitigate neuroinflammatory …
L Fornari Laurindo, J Aparecido Dias… - Frontiers in …, 2024 - frontiersin.org
The increasing life expectancy has led to a higher incidence of age-related
neurodegenerative conditions. Within this framework, neuroinflammation emerges as a …
neurodegenerative conditions. Within this framework, neuroinflammation emerges as a …
Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling
Nucleus pulposus (NP) cells reside in the avascular and hypoxic microenvironment of
intervertebral discs. Importantly, many activities related to survival and function of NP cells …
intervertebral discs. Importantly, many activities related to survival and function of NP cells …
Endometrial cancer stem cells: where do we stand and where should we go?
C Banz-Jansen, LP Helweg, B Kaltschmidt - International Journal of …, 2022 - mdpi.com
Endometrial cancer is one of the most common malignant diseases in women worldwide,
with an incidence of 5.9%. Thus, it is the most frequent cancer of the female genital tract, with …
with an incidence of 5.9%. Thus, it is the most frequent cancer of the female genital tract, with …
Role of HIF-1α/ERRα in enhancing cancer cell metabolism and promoting resistance of endometrial cancer cells to pyroptosis
P Su, L Yu, X Mao, P Sun - Frontiers in Oncology, 2022 - frontiersin.org
Oxygen is critical to energy metabolism, and tumors are often characterized by a hypoxic
microenvironment. Owing to the high metabolic energy demand of malignant tumor cells …
microenvironment. Owing to the high metabolic energy demand of malignant tumor cells …
Prolyl-4-hydroxylase domain protein 2 controls NF-κB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus …
J Li, W Yuan, S Jiang, W Ye, H Yang, IM Shapiro… - Journal of Biological …, 2015 - ASBMB
Prolyl-4-hydroxylase (PHD) proteins are key in sensing tissue hypoxia. In nucleus pulposus
(NP) cells, our previous work demonstrated that PHD isoforms have a differential …
(NP) cells, our previous work demonstrated that PHD isoforms have a differential …