New insights on pharmacological and therapeutic potentials of trimetazidine beyond anti-anginal drug: A comprehensive review

D Singh, J Oladimeji-Salami, AJ Akindele - European Journal of …, 2024 - Elsevier
Trimetazidine (TMZ) is a beneficial and well-tolerable anti-anginal drug which has protective
action towards ischemia and reperfusion injury. TMZ performs its anti-ischemic effect by …

Anti‐oxidant activity mediated neuroprotective potential of trimetazidine on focal cerebral ischaemia–reperfusion injury in rats

V Dhote, R Balaraman - Clinical and Experimental …, 2008 - Wiley Online Library
SUMMARY 1 The present study was designed to investigate the neuroprotective effect of
trimetazidine (TMZ) following focal cerebral ischaemia–reperfusion (I/R) injury in rat …

[HTML][HTML] Trimetazidine attenuates high-altitude fatigue and cardiorespiratory fitness impairment: a randomized double-blinded placebo-controlled clinical trial

J Yang, L Zhang, C Liu, J Zhang, S Yu, J Yu… - Biomedicine & …, 2019 - Elsevier
Trimetazidine (TMZ) has been shown to optimize myocardial energy metabolism and is a
common anti-ischemic agent. Our trial (ChiCTR-TRC-13003298) aimed to explore whether …

[PDF][PDF] Trimetazidine increases [3 H] glucose uptake in rat brain

RS Szczerbak, J Niwiñski, J Gorza³ek… - Pharmacological …, 2006 - if-pan.krakow.pl
Trimetazidine, a clinically effective antianginal agent with no negative inotropic or vascular
properties, acts by optimizing cardiac energy metabolism through inhibition of free faty acid …

[PDF][PDF] Применение Тримектала в терапии хронической недостаточности мозгового кровообращения

ЕГ Клочева, ЕБ Фомина, АВ Комяхов - Психиатрия, 2009 - vertex.spb.ru
В отечественной классификации сосудистых заболеваний головного мозга под
термином «дисциркуляторная энцефалопатия» понимают прогрессирующую …

Application of evoked potential in acute stroke in rats

S Yang - 2009 3rd International Conference on Bioinformatics …, 2009 - ieeexplore.ieee.org
The aim of this paper is to study the characteristic of latency of evoked potential and
monitoring brain function following acute ischemic stroke in rats. The model of acute …

Changes of evoked potential and expression of nestin in subventricular zones in rats after focal cerebral ischemia

GAO Jie, Y WANG, L WANG, Z Ling, Y WU… - Journal of Medical …, 2007 - Elsevier
OBJECTIVE: To study the characteristics of latency of somatosensory evoked potential
(SEP) and motor evoked potential (MEP) and the expression of nestin in subventricular …

Funkční důsledky epileptických záchvatů a hypoxicko-ischemického poškození CNS

D Krýsl - 2013 - dspace.cuni.cz
Hypoxicko-ischemické postižení CNS a epileptické záchvaty mají řadu společnych
patofyziologickych rysů. Základní mechanismy, ať už poškozující (excitotoxicita, volné …

[PDF][PDF] РУССКИЙ МЕДИЦИНСКИЙ

ЮН Гришкин, ТН Новикова, ТВ Тюрина, ЕГ Клочева - vertex-spb.ru
Самой частой причиной болезней и смерти людей в современном мире является
атеросклероз. Его прогрессирование приводит к поражению все новых сосудистых …

[引用][C] 诱发电位评价缺血性中风后脑功能的实验研究

邵阳, 高洁, 杨期东 - 中国医学物理学杂志, 2009