N-Heterocyclic carbenes (NHCs) have become one of the most widely studied class of
ligands in molecular chemistry and have found applications in fields as varied as catalysis …

N-Heterocyclic carbenes (NHCs) are cyclic carbenes bearing at least one R-amino
substituent. 1 The most common subclasses of NHCs are represented in Chart 1. Early work …

A brief account of the major developments of palladium-catalyzed cross-coupling during the
last two decades is highlighted chronologically, with an emphasis on the personal …

Quantification and variation of characteristic properties of different ligand classes is an
exciting and rewarding research field. N‐Heterocyclic carbenes (NHCs) are of special …

Electronic and steric ligand effects both play major roles in organometallic chemistry and
consequently in metal-mediated catalysis. Quantifying such parameters is of interest to …

Strategies for the development of Pd catalysts based on utilization of L2Pd and LPd species,
beyond the contributions of the 2010 Nobel Laureates Richard Heck, Ei-ichi Negishi, and …

The discovery and investigation of ligand-modulated Pd-catalyzed aerobic alcohol
oxidations is documented. The project has evolved from a simple empirical discovery that (−) …

Indoles are ubiquitous bioactive heterocycles in nature.[1] Their importance in medicinal
chemistry has stimulated considerable interest from organic chemists, and has encouraged …

Ruthenium-catalyzed oxidative cyanation of tertiary amines with molecular oxygen in the
presence of sodium cyanide and acetic acid gives the corresponding α-aminonitriles, which …

The discovery of NHCs (NHC= N‐heterocyclic carbenes) as ancillary ligands in transition‐
metal‐catalysis ranks as one of the most important developments in synthesis and catalysis …