Long non-coding RNAs in the regulation of gene expression: physiology and disease
JCR Fernandes, SM Acuña, JI Aoki, LM Floeter-Winter… - Non-coding RNA, 2019 - mdpi.com
The identification of RNAs that are not translated into proteins was an important
breakthrough, defining the diversity of molecules involved in eukaryotic regulation of gene …
breakthrough, defining the diversity of molecules involved in eukaryotic regulation of gene …
History, discovery, and classification of lncRNAs
J Jarroux, A Morillon, M Pinskaya - Long non coding RNA biology, 2017 - Springer
Abstract The RNA World Hypothesis suggests that prebiotic life revolved around RNA
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …
When long noncoding becomes protein coding
CCR Hartford, A Lal - Molecular and cellular biology, 2020 - Taylor & Francis
Recent advancements in genetic and proteomic technologies have revealed that more of the
genome encodes proteins than originally thought possible. Specifically, some putative long …
genome encodes proteins than originally thought possible. Specifically, some putative long …
Structured elements drive extensive circular RNA translation
The human genome encodes tens of thousands circular RNAs (circRNAs) with mostly
unknown functions. Circular RNAs require internal ribosome entry sites (IRES) if they are to …
unknown functions. Circular RNAs require internal ribosome entry sites (IRES) if they are to …
Control of gene expression through the nonsense-mediated RNA decay pathway
A Nickless, JM Bailis, Z You - Cell & bioscience, 2017 - Springer
Nonsense-mediated RNA decay (NMD) was originally discovered as a cellular surveillance
pathway that safeguards the quality of mRNA transcripts in eukaryotic cells. In its canonical …
pathway that safeguards the quality of mRNA transcripts in eukaryotic cells. In its canonical …
LncRNA-encoded peptide: functions and predicting methods
Long non-coding RNA (lncRNA) was originally defined as the representative of the non-
coding RNAs and unable to encode. However, recent reports suggest that some lncRNAs …
coding RNAs and unable to encode. However, recent reports suggest that some lncRNAs …
The affinity of the S9. 6 antibody for double-stranded RNAs impacts the accurate mapping of R-loops in fission yeast
SR Hartono, A Malapert, P Legros, P Bernard… - Journal of molecular …, 2018 - Elsevier
R-loops, which result from the formation of stable DNA: RNA hybrids, can both threaten
genome integrity and act as physiological regulators of gene expression and chromatin …
genome integrity and act as physiological regulators of gene expression and chromatin …
RNA folding and functions of RNA helicases in ribosome biogenesis
V Mitterer, B Pertschy - RNA biology, 2022 - Taylor & Francis
Eukaryotic ribosome biogenesis involves the synthesis of ribosomal RNA (rRNA) and its
stepwise folding into the unique structure present in mature ribosomes. rRNA folding starts …
stepwise folding into the unique structure present in mature ribosomes. rRNA folding starts …
The DDX5/Dbp2 subfamily of DEAD‐box RNA helicases
The mammalian DEAD‐box RNA helicase DDX5, its paralog DDX17, and their orthologs in
Saccharomyces cerevisiae and Drosophila melanogaster, namely Dbp2 and Rm62, define a …
Saccharomyces cerevisiae and Drosophila melanogaster, namely Dbp2 and Rm62, define a …
Functional micropeptides encoded by long non-coding RNAs: a comprehensive review
J Pan, R Wang, F Shang, R Ma, Y Rong… - Frontiers in molecular …, 2022 - frontiersin.org
Long non-coding RNAs (lncRNAs) were originally defined as non-coding RNAs (ncRNAs)
which lack protein-coding ability. However, with the emergence of technologies such as …
which lack protein-coding ability. However, with the emergence of technologies such as …