This article summarizes recent experimental and epidemiological data on the toxic and
beneficial effects of ethanol and its metabolites (acetaldehyde), and focuses on their …

Fibrosis, seen in the liver, lung, heart, kidney, and skin, is a significant global disease
burden. Currently, therapeutic treatment is limited, and the number of cases continues to …

Development of a suitable mouse model would facilitate the investigation of
pathomechanisms underlying human psoriasis and would also assist in development of …

Objectives: The purpose of this study was to examine the cellular and molecular
mechanisms underlying alcoholic cardiomyopathy. Background: The mechanism for …

The role of resistance training on collagen deposition, the inflammatory profile and muscle
weakness in heart failure remains unclear. Therefore, this study evaluated the influence of a …

TEA domain transcription factor-1 (TEAD-1) is essential for proper heart development and is
implicated in cardiac specific gene expression and the hypertrophic response of primary …

Background The condition known as cachexia presents in most patients with malignant
tumours, leading to a poor quality of life and premature death. Although the cancer‐cachexia …

We studied the protective effect of stromal cell-derived factor-1β (SDF-1β) on cardiac cells
from lipotoxicity in vitro and diabetes in vivo. Exposure of cardiac cells to palmitate increased …

Excess cardiac iron levels are associated with cardiac damage and can result in increased
morbidity and mortality. Here, we hypothesize that elevations in tissue iron can activate …

Mitochondria are subcellular organelles that provide energy for the cell. They form a
dynamic tubular network and play an important role in maintaining the cell function and …