Bacillus subtilis, belonging to the type species of Bacillus, is a type of soil-derived, low% G+
C, endospore-forming Gram-positive bacterium. After the discovery of B. subtilis 168 that …

Bacillus subtilis is a successful host for producing recombinant proteins. Its GRAS (generally
recognized as safe) status and its remarkable innate ability to absorb and incorporate …

Dynamic regulation is a promising strategy for fine-tuning metabolic fluxes in microbial cell
factories. However, few of these synthetic regulatory systems have been developed for …

Glucose and xylose are the two most abundant sugars in renewable lignocellulose sources;
however, typically they cannot be simultaneously utilized due to carbon catabolite …

Abstract Background The Gram-positive bacterium Bacillus subtilis has been widely used as
a cell factory for the production of proteins due to its generally regarded as safe (GRAS) …

Background Bacillus subtilis is developed to be an attractive expression host to produce
both secreted and cytoplasmic proteins owing to its prominent biological characteristics …

Growth and survival are key determinants of bacterial fitness. However, how resource
allocation of bacteria could reconcile these two traits to maximize fitness remains poorly …

A novel inducible gene expression system using p-isopropyl benzoate (cumate) as an
inducer was developed for the industrial production hosts, Bacillus subtilis and Bacillus …

The ganA gene from Bacillus subtilis encoding a β-galactosidase for degradation of the
galactomannan was integrated in different loci of the B. subtilis chromosome employing the …

The trade-off between rapid growth and other important physiological traits (eg, survival and
adaptability) poses a fundamental challenge for microbes to achieve fitness maximization …