Autologous chimeric antigen receptor (CAR) T cells have changed the therapeutic
landscape in haematological malignancies. Nevertheless, the use of allogeneic CAR T cells …

Adoptive cellular immunotherapy using immune cells expressing chimeric antigen receptors
(CARs) has shown promise, particularly for the treatment of hematological malignancies. To …

▪ Abstract This review summarizes the major features of CD1 genes and proteins, the
patterns of intracellular trafficking of CD1 molecules, and how they sample different …

CD1d-restricted natural killer (NK) T cells are known to potently secrete T helper (Th) 1 and
Th2 cytokines and to mediate cytolysis, but it is unclear how these contrasting functional …

Invariant natural killer T cells (i NKT cells) have a prominent role during infection and other
inflammatory processes, and these cells can be activated through their T cell antigen …

Chimeric antigen receptor anti-CD19 (CAR19)-T cell immunotherapy-induced clinical
remissions in CD19+ B cell lymphomas are often short lived. We tested whether CAR19 …

Abstract Purpose: Invariant NKT cells (iNKT) are innate-like CD1d-restricted T cells with
immunoregulatory activity in diseases including cancer. iNKT from advanced cancer patients …

Invariant NK T cells express certain NK cell receptors and an invariant TCRα chain specific
for the MHC class I-like CD1d protein. These invariant NK T cells can regulate diverse …

Several transplant patients maintain stable kidney graft function in the absence of
immunosuppression. Here we compared the characteristics of their peripheral B cells to that …

To evaluate the safety, immune responses, and antitumor responses after the administration
of α-galactosylceramide (αGalCer) KRN7000-pulsed PBMC cultured with IL-2 and GM-CSF …