Colonization, Infection, and the Accessory Genome of Klebsiella pneumoniae

RM Martin, MA Bachman - Frontiers in cellular and infection …, 2018 - frontiersin.org
Klebsiella pneumoniae is a Gram-negative pathogen that has a large accessory genome of
plasmids and chromosomal gene loci. This accessory genome divides K. pneumoniae …

[HTML][HTML] A global perspective on the convergence of hypervirulence and carbapenem resistance in Klebsiella pneumoniae

P Lan, Y Jiang, J Zhou, Y Yu - Journal of global antimicrobial resistance, 2021 - Elsevier
Hypervirulence and carbapenem resistance have emerged as two distinct evolutionary
directions for Klebsiella pneumoniae, which pose a great threat in clinical settings. Multiple …

Virulence Factors in Hypervirulent Klebsiella pneumoniae

J Zhu, T Wang, L Chen, H Du - Frontiers in microbiology, 2021 - frontiersin.org
Hypervirulent Klebsiella pneumoniae (hvKP) has spread globally since first described in the
Asian Pacific Rim. It is an invasive variant that differs from the classical K. pneumoniae …

Antimicrobial Resistance of Hypervirulent Klebsiella pneumoniae: Epidemiology, Hypervirulence-Associated Determinants, and Resistance Mechanisms

CR Lee, JH Lee, KS Park, JH Jeon, YB Kim… - Frontiers in cellular …, 2017 - frontiersin.org
Klebsiella pneumoniae is one of the most clinically relevant species in immunocompromised
individuals responsible for community-acquired and nosocomial infections, including …

Hypervirulent (hypermucoviscous) Klebsiella pneumoniae A new and dangerous breed

AS Shon, RPS Bajwa, TA Russo - Virulence, 2013 - Taylor & Francis
A new hypervirulent (hypermucoviscous) variant of Klebsiella pneumoniae has emerged.
First described in the Asian Pacific Rim, it now increasingly recognized in Western countries …

Klebsiella pneumoniae liver abscess: a new invasive syndrome

LK Siu, KM Yeh, JC Lin, CP Fung… - The Lancet infectious …, 2012 - thelancet.com
Klebsiella pneumoniae is a well known human nosocomial pathogen. Most community-
acquired K pneumoniae infections cause pneumonia or urinary tract infections. During the …

Hypervirulent klebsiella pneumoniae

TA Russo, CM Marr - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Hypervirulent K. pneumoniae (hvKp) is an evolving pathotype that is more virulent than
classical K. pneumoniae (cKp). hvKp usually infects individuals from the community, who are …

Capsule type defines the capability of Klebsiella pneumoniae in evading Kupffer cell capture in the liver

X Huang, X Li, H An, J Wang, M Ding, L Wang… - PLoS …, 2022 - journals.plos.org
Polysaccharide capsule is the main virulence factor of K. pneumoniae, a major pathogen of
bloodstream infections in humans. While more than 80 capsular serotypes have been …

Population genomics of hypervirulent Klebsiella pneumoniae clonal-group 23 reveals early emergence and rapid global dissemination

MMC Lam, KL Wyres, S Duchêne, RR Wick… - Nature …, 2018 - nature.com
Severe liver abscess infections caused by hypervirulent clonal-group CG23 Klebsiella
pneumoniae have been increasingly reported since the mid-1980s. Strains typically possess …

Finding order in the chaos: outstanding questions in Klebsiella pneumoniae pathogenesis

S Gonzalez-Ferrer, HF Peñaloza, JA Budnick… - Infection and …, 2021 - Am Soc Microbiol
Klebsiella pneumoniae are Gram-negative facultative anaerobes that are found within host-
associated commensal microbiomes, but they can also cause a wide range of infections that …