Protein post-translational modification (PTM) is a covalent process that occurs in proteins
during or after translation through the addition or removal of one or more functional groups …

Despite recent progress in understanding the cancer genome, there is still a relative delay in
understanding the full aspects of the glycome and glycoproteome of cancer. Glycobiology …

Aberrant glycosylation plays a fundamental role in key pathological steps of tumour
development and progression. Glycans have roles in cancer cell signalling, tumour cell …

Tumour metastasis is the main cause of cancer related deaths. Metastasis is an intricate
multi-step process that requires the acquisition of several cancer cell features, including the …

Background The majority of human proteins are being modified by covalent attachment of
complex oligosaccharides—glycans. Both glycans and polypeptide parts of a protein …

E‐cadherin protein (CDH1 gene) integrity is fundamental to the process of epithelial
polarization and differentiation. Deregulation of the E‐cadherin function plays a crucial role …

Glycans are sequences of carbohydrates that are added to proteins or lipids to modulate
their structure and function. Glycans modify proteins required for regulation of immune cells …

Background While the underlying causes of cancer are genetic modifications, changes in
cellular states mediate cancer development. Tumor cells display markedly changed …

Background This study aimed to investigate the expression and clinical significance of
Dendritic cell-associated C-type lectin-1 (Dectin-1) in gastric cancer (GC), and to explore the …

Gastric cancer (GC) is a highly malignant disease affecting humans worldwide and has a
poor prognosis. Most GC cases are detected at advanced stages due to the cancer lacking …