Molecular mechanisms of chemotropism and cell fusion in unicellular fungi

SG Martin - Journal of cell science, 2019 - journals.biologists.com
In all eukaryotic phyla, cell fusion is important for many aspects of life, from sexual
reproduction to tissue formation. Fungal cells fuse during mating to form the zygote, and …

Recent progress in the development of droplet-based microfluidic technologies for phenotypic screening using cell-cell interactions

S Kim, JH Moon, GY Jung - Biotechnology and Bioprocess Engineering, 2023 - Springer
Specific cell-cell interactions enable the complex metabolic tasks associated with natural
microbial communities and facilitates their improved adaptation to environmental changes …

An arbitrary Lagrangian Eulerian smoothed particle hydrodynamics (ALE-SPH) method with a boundary volume fraction formulation for fluid-structure interaction

B Jacob, B Drawert, TM Yi, L Petzold - Engineering analysis with boundary …, 2021 - Elsevier
We present a new weakly-compressible smoothed particle hydrodynamics (SPH) method
capable of modeling non-slip fixed and moving wall boundary conditions. The formulation …

RGS proteins and septins cooperate to promote chemotropism by regulating polar cap mobility

JB Kelley, G Dixit, JB Sheetz, SP Venkatapurapu… - Current Biology, 2015 - cell.com
Background Septins are well known to form a boundary between mother and daughter cells
in mitosis, but their role in other morphogenic states is poorly understood. Results Using …

Functions for Cdc42p BEM adaptors in regulating a differentiation-type MAP kinase pathway

S Basu, B González, B Li, G Kimble… - Molecular biology of …, 2020 - Am Soc Cell Biol
Ras homology (Rho) GTPases regulate cell polarity and signal transduction pathways to
control morphogenetic responses in different settings. In yeast, the Rho GTPase Cdc42p …

Programmable static droplet array for the analysis of cell–cell communication in a confined microenvironment

SH Jin, SS Lee, B Lee, SG Jeong, M Peter… - Analytical …, 2017 - ACS Publications
Direct cell–cell communication can occur through various chemical and mechanical signals.
However, available cell culture systems lack single-cell resolution and are often limited by …

Exploratory polarization facilitates mating partner selection in Saccharomyces cerevisiae

MR Clark-Cotton, NT Henderson, M Pablo… - Molecular biology of …, 2021 - Am Soc Cell Biol
Yeast decode pheromone gradients to locate mating partners, providing a model for
chemotropism. How yeast polarize toward a single partner in crowded environments is …

Quantitative analysis of the yeast pheromone pathway

JP Shellhammer, AE Pomeroy, Y Li, L Dujmusic… - Yeast, 2019 - Wiley Online Library
The pheromone response pathway of the yeast Saccharomyces cerevisiae is a well‐
established model for the study of G proteins and mitogen‐activated protein kinase (MAPK) …

A predictive model for yeast cell polarization in pheromone gradients

N Muller, M Piel, V Calvez, R Voituriez… - PLoS computational …, 2016 - journals.plos.org
Author Summary Budding yeast cells exist in two mating types, a and α, which use peptide
pheromones to communicate with each other during mating. Mating depends on the ability …

A Model for Direction Sensing in Dictyostelium discoideum: Ras Activity and Symmetry Breaking Driven by a Gβγ-Mediated, Gα2-Ric8 -- Dependent Signal …

Y Cheng, H Othmer - PLoS computational biology, 2016 - journals.plos.org
Chemotaxis is a dynamic cellular process, comprised of direction sensing, polarization and
locomotion, that leads to the directed movement of eukaryotic cells along extracellular …