[HTML][HTML] Antigenic evolution of SARS coronavirus 2

AZ Mykytyn, RAM Fouchier, BL Haagmans - Current Opinion in Virology, 2023 - Elsevier
SARS coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, emerged in China in
December 2019. Vaccines developed were very effective initially, however, the virus has …

[HTML][HTML] A systematic review and meta-analysis on the real-world effectiveness of COVID-19 vaccines against infection, symptomatic and severe COVID-19 disease …

H Mohammed, DD Pham-Tran, ZYM Yeoh, B Wang… - Vaccines, 2023 - mdpi.com
Real-world data on the effectiveness of COVID-19 vaccines against the Omicron variant (B.
1.1. 529) is limited. This systematic review aimed to investigate the real-world effectiveness …

Mapping SARS-CoV-2 antigenic relationships and serological responses

SH Wilks, B Mühlemann, X Shen, S Türeli… - Science, 2023 - science.org
During the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic,
multiple variants escaping preexisting immunity emerged, causing reinfections of previously …

[HTML][HTML] BA. 2 and BA. 5 omicron differ immunologically from both BA. 1 omicron and pre-omicron variants

A Rössler, A Netzl, L Knabl, H Schäfer, SH Wilks… - Nature …, 2022 - nature.com
Several studies have shown that SARS-CoV-2 BA. 1 omicron is an immune escape variant.
Meanwhile, however, omicron BA. 2 and BA. 5 became dominant in many countries and …

[HTML][HTML] Seroprevalence of anti-SARS-CoV-2 antibodies and cross-variant neutralization capacity after the Omicron BA. 2 wave in Geneva, Switzerland: a population …

ME Zaballa, J Perez-Saez, C de Mestral… - The Lancet Regional …, 2023 - thelancet.com
Background More than two years into the COVID-19 pandemic, most of the population has
developed anti-SARS-CoV-2 antibodies from infection and/or vaccination. However, public …

[HTML][HTML] B-cell and antibody responses to SARS-CoV-2: infection, vaccination, and hybrid immunity

D Lapuente, TH Winkler, M Tenbusch - Cellular & Molecular …, 2024 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019
prompted scientific, medical, and biotech communities to investigate infection-and vaccine …

A spike-trimer protein-based tetravalent COVID-19 vaccine elicits enhanced breadth of neutralization against SARS-CoV-2 Omicron subvariants and other variants

R Wang, H Huang, C Yu, C Sun, J Ma, D Kong… - Science China Life …, 2023 - Springer
Multivalent vaccines combining crucial mutations from phylogenetically divergent variants
could be an effective approach to defend against existing and future SARS-CoV-2 variants …

[HTML][HTML] Distinct receptor binding domain IgG thresholds predict protective host immunity across SARS-CoV-2 variants and time

G Kenny, S O'Reilly, N Wrigley Kelly, R Negi… - Nature …, 2023 - nature.com
SARS-CoV-2 neutralising antibodies provide protection against COVID-19. Evidence from
early vaccine trials suggested binding antibody thresholds could serve as surrogate markers …

Comparative analysis of SARS-CoV-2 neutralization titers reveals consistency between human and animal model serum and across assays

B Mühlemann, SH Wilks, L Baracco, M Bekliz… - Science Translational …, 2024 - science.org
The evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) requires
ongoing monitoring to judge the ability of newly arising variants to escape the immune …

Primary exposure to SARS-CoV-2 via infection or vaccination determines mucosal antibody-dependent ACE2 binding inhibition

J Fröberg, VJCH Koomen… - The Journal of …, 2024 - academic.oup.com
Background Mucosal antibodies play a critical role in preventing SARS-CoV-2 infections or
reinfections by blocking the interaction of the receptor-binding domain (RBD) with the …