Mechanisms of autoantibody-induced pathology

RJ Ludwig, K Vanhoorelbeke, F Leypoldt… - Frontiers in …, 2017 - frontiersin.org
Autoantibodies are frequently observed in healthy individuals. In a minority of these
individuals, they lead to manifestation of autoimmune diseases, such as rheumatoid arthritis …

Autoimmune subepidermal bullous diseases of the skin and mucosae: clinical features, diagnosis, and management

KT Amber, DF Murrell, E Schmidt, P Joly… - Clinical reviews in allergy …, 2018 - Springer
Autoimmune subepidermal blistering diseases of the skin and mucosae constitute a large
group of sometimes devastating diseases, encompassing bullous pemphigoid, gestational …

Dermatological manifestations in inflammatory bowel diseases

E Antonelli, G Bassotti, M Tramontana… - Journal of clinical …, 2021 - mdpi.com
Inflammatory bowel diseases (IBDs) may be associated with extra-intestinal manifestations.
Among these, mucocutaneous manifestations are relatively frequent, often difficult to …

Clinical features and diagnosis of epidermolysis bullosa acquisita

A Vorobyev, RJ Ludwig, E Schmidt - Expert review of clinical …, 2017 - Taylor & Francis
Introduction: Epidermolysis bullosa acquisita (EBA) is a rare autoimmune blistering disease
of skin and mucous membranes. EBA is caused by autoantibodies against type VII collagen …

The critical role of C5a as an initiator of neutrophil-mediated autoimmune inflammation of the joint and skin

CD Sadik, Y Miyabe, T Sezin, AD Luster - Seminars in immunology, 2018 - Elsevier
The deposition of IgG autoantibodies in peripheral tissues and the subsequent activation of
the complement system, which leads to the accumulation of the anaphylatoxin C5a in these …

Unraveling the ECM-immune cell crosstalk in skin diseases

O Bhattacharjee, U Ayyangar, AS Kurbet… - Frontiers in cell and …, 2019 - frontiersin.org
The extracellular matrix (ECM) is a complex network of proteins and proteoglycans secreted
by keratinocytes, fibroblasts and immune cells. The function of the skin ECM has expanded …

Meta-analysis of the clinical and immunopathological characteristics and treatment outcomes in epidermolysis bullosa acquisita patients

H Iwata, A Vorobyev, H Koga, A Recke… - Orphanet journal of rare …, 2018 - Springer
Background Epidermolysis bullosa acquisita (EBA) is an orphan autoimmune disease.
Several clinical phenotypes have been described, but subepidermal blistering is …

Epidermolysis bullosa acquisita: A comprehensive review

K Kridin, D Kneiber, EH Kowalski, M Valdebran… - Autoimmunity …, 2019 - Elsevier
Epidermolysis bullosa acquisita is a rare autoimmune blistering disease which results in
vesicle and bullae formation on the skin and erosions on the mucous membranes. EBA is …

Regulatory T-cell deficiency leads to pathogenic bullous pemphigoid antigen 230 autoantibody and autoimmune bullous disease

S Haeberle, X Wei, K Bieber, S Goletz… - Journal of Allergy and …, 2018 - Elsevier
Background Autoimmune bullous diseases/dermatoses (AIBDs) are severe autoantibody-
mediated skin diseases. The pathogenic relevance of autoreactive CD4+ T cells for the …

Epidermolysis bullosa acquisita

D Miyamoto, JO Gordilho, CG Santi… - Anais Brasileiros de …, 2022 - SciELO Brasil
Epidermolysis bullosa acquisita is a rare autoimmune disease, characterized by the
synthesis of anti-collagen VII autoantibodies, the main component of hemidesmosome …