Comprehensive Analysis and Comparison on the Codon Usage Pattern of Whole Mycobacterium tuberculosis Coding Genome from Different Area

L Gun, R Yumiao, P Haixian… - BioMed Research …, 2018 - Wiley Online Library
Phenomenon of unequal use of synonymous codons in Mycobacterium tuberculosis is
common. Codon usage bias not only plays an important regulatory role at the level of gene …

Translation-associated mutational U-pressure in the first ORF of SARS-CoV-2 and other coronaviruses

VV Khrustalev, R Giri, TA Khrustaleva… - Frontiers in …, 2020 - frontiersin.org
Within 4 months of the ongoing COVID-19 pandemic caused by SARS-CoV-2, more than
250 nucleotide mutations have been detected in ORF1ab of the virus isolated from infected …

Novel Mutations in pncA Gene of Pyrazinamide Resistant Clinical Isolates of Mycobacterium tuberculosis

M Kahbazi, H Sarmadian, A Ahmadi, F Didgar… - Scientia …, 2018 - mdpi.com
In clinical isolates of Mycobacterium tuberculosis (MTB), resistance to pyrazinamide occurs
by mutations in any positions of the pncA gene (NC_000962. 3) especially in nucleotides …

Decoding Multidrug Resistance: Genetic Architecture and Codon Usage Patterns in ESKAPE Pathogens

U Dahal, A Bansal, D Chitara - Current Pharmacogenomics and …, 2024 - benthamdirect.com
Introduction The escalating challenge of multidrug resistance among ESKAPE pathogens
has become a prominent concern for global healthcare providers, leading to amplified …

The history of mutational pressure changes during the evolution of adeno-associated viruses: A message to gene therapy and DNA-vaccine vectors designers

VV Khrustalev, TA Khrustaleva, AN Stojarov… - Infection, Genetics and …, 2020 - Elsevier
The use of virus-associated vectors for gene therapy and vaccination have emerged as safe
and effective delivery system. Like all other genetic materials, these vehicles are also prone …

Transmission Electron Microscopy of XDR Mycobacterium tuberculosis Isolates Grown on High Dose of Ofloxacin

M Arjomandzadegan, M Sadrnia, L Titov… - Scientia …, 2017 - mdpi.com
The aim of the study was to investigate behavior of resistant Mycobacterium tuberculosis
(MTB) isolates under a high dose of ofloxacin and its morphological changes. 19 extensively …

Germline mutations directions are different between introns of the same gene: case study of the gene coding for amyloid-beta precursor protein

VV Khrustalev, TA Khrustaleva, AV Popinako - Genetica, 2023 - Springer
Amyloid-beta precursor protein (APP) is highly conserved in mammals. This feature allowed
us to compare nucleotide usage biases in fourfold degenerated sites along the length of its …

Comprehensive analysis and comparison on the codon usage pattern of whole Mycobacterium tuberculosis coding genome from different area

G Li, R Yumiao, P Haixian… - BioMed Research …, 2018 - search.proquest.com
Phenomenon of unequal use of synonymous codons in Mycobacterium tuberculosis is
common. Codon usage bias not only plays an important regulatory role at the level of gene …

[PDF][PDF] The influence of ethanol on pyruvate kinases activity in vivo, in vitro, in silico

LS Vladimirovich, KV Victorovich… - American Journal of …, 2013 - Citeseer
The influence of ethanol on enzymatic activities of muscle and liver pyruvate kinases has
been studied in rats in series of in vivo and in vitro experiments accompanied by in silico …

[HTML][HTML] Short repeats in the spa gene of Staphylococcus aureus are prone to nonsense mutations: stop codons can be found in strains isolated from patients with …

VV Khrustalev, E Ghaznavi-Rad, V Neela… - Research in …, 2013 - Elsevier
Fifteen sequences with stop codons have been obtained in the course of standard
methicillin-resistant Staphylococcus aureus (MRSA) spa typing. In nine of those sequences …