Immune responses to Marek's disease virus infection

KA Schat, CJ Markowski-Grimsrud - Marek's Disease, 2001 - Springer
Abstract Marek's disease (MD), a herpesvirus-induced lymphomatous disease in chickens,
has attracted the interest of immunologists since MD virus (MDV) was isolated in 1968 and …

[HTML][HTML] Paroxysmal nocturnal haemoglobinuria: nature's gene therapy?

RJ Johnson, P Hillmen - Molecular Pathology, 2002 - ncbi.nlm.nih.gov
The development of paroxysmal nocturnal haemoglobinuria (PNH) requires two coincident
factors: somatic mutation of the PIG-A gene in one or more haemopoietic stem cells and an …

Complete, long-lasting protection against lethal infectious bursal disease virus challenge by a single vaccination with an avian herpesvirus vector expressing VP2 …

K Tsukamoto, S Saito, S Saeki, T Sato… - Journal of …, 2002 - Am Soc Microbiol
Marek's disease herpesvirus is a vaccine vector of great promise for chickens; however,
complete protection against foreign infectious diseases has not been achieved. In this study …

Neoplastic diseases

V Nair, I Gimeno, J Dunn, G Zavala… - Diseases of …, 2020 - Wiley Online Library
This chapter deals primarily with the three most economically important virus‐induced
transmissible neoplastic diseases of poultry, namely: the herpesvirus‐induced Marek's …

Vaccination against Marek's disease

M Bublot, J Sharma - Marek's Disease, 2004 - Elsevier
Publisher Summary This chapter discusses the use of vaccinations as a prevention measure
against Marek's disease (MD). The MD vaccines have brought enormous benefits to poultry …

Development of an effective polyvalent vaccine against both Marek's and Newcastle diseases based on recombinant Marek's disease virus type 1 in commercial …

K Sonoda, M Sakaguchi, H Okamura… - Journal of …, 2000 - Am Soc Microbiol
An earlier report (M. Sakaguchi et al., Vaccine 16: 472–479, 1998) showed that recombinant
Marek's disease virus type 1 (rMDV1) expressing the fusion (F) protein of Newcastle disease …

A MEQ-deleted Marek's disease virus cloned as a bacterial artificial chromosome is a highly efficacious vaccine

RF Silva, JR Dunn, HH Cheng, M Niikura - Avian Diseases, 2010 - meridian.allenpress.com
The Marek's disease virus (MDV) induces T-cell tumors in susceptible chickens. Of the 80 to
100 known MDV genes, only the MDV MEQ gene was shown to have transforming …

HVT-vectored H7 vaccine protects chickens from lethal infection with the highly pathogenic H7N9 Avian influenza virus

Y Chen, G Su, J Zhang, B Li, K Ma, X Zhang… - Veterinary …, 2023 - Elsevier
Since mid-2016, the highly pathogenic H7N9 subtype avian influenza virus (AIV) has
threatened both public health and the poultry industry. Although a vaccination strategy has …

Expression of HA of HPAI H5N1 virus at US2 gene insertion site of turkey herpesvirus induced better protection than that at US10 gene insertion site

H Gao, H Cui, X Cui, X Shi, Y Zhao, X Zhao, Y Quan… - PLoS …, 2011 - journals.plos.org
Herpesvirus of turkey (HVT) is being widely used as a vector for development of
recombinant vaccines and US2 and US10 genes are often chosen as insertion sites for …

Avirulent Marek's disease virus type 1 strain 814 vectored vaccine expressing avian influenza (AI) virus H5 haemagglutinin induced better protection than turkey …

H Cui, H Gao, X Cui, Y Zhao, X Shi, Q Li, S Yan, M Gao… - PloS one, 2013 - journals.plos.org
Background Herpesvirus of turkey (HVT) as a vector to express the haemagglutinin (HA) of
avian influenza virus (AIV) H5 was developed and its protection against lethal Marek's …