The road to metagenomics: from microbiology to DNA sequencing technologies and bioinformatics

A Escobar-Zepeda, A Vera-Ponce de León… - Frontiers in …, 2015 - frontiersin.org
The study of microorganisms that pervade each and every part of this planet has
encountered many challenges through time such as the discovery of unknown organisms …

Metagenome analysis: a powerful tool for enzyme bioprospecting

A Madhavan, R Sindhu, B Parameswaran… - Applied biochemistry …, 2017 - Springer
Microorganisms are found throughout every corner of nature, and vast number of
microorganisms is difficult to cultivate by classical microbiological techniques. The advent of …

[PDF][PDF] MicrobiomeAnalyst: a web-based tool for comprehensive statistical, visual and meta-analysis of microbiome data

A Dhariwal, J Chong, S Habib, IL King… - Nucleic acids …, 2017 - academic.oup.com
The widespread application of next-generation sequencing technologies has revolutionized
microbiome research by enabling high-throughput profiling of the genetic contents of …

Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome

O Rom, Y Liu, Z Liu, Y Zhao, J Wu, A Ghrayeb… - Science translational …, 2020 - science.org
Nonalcoholic fatty liver disease (NAFLD) including nonalcoholic steatohepatitis (NASH) has
reached epidemic proportions with no pharmacological therapy approved. Lower circulating …

[HTML][HTML] Bioconductor workflow for microbiome data analysis: from raw reads to community analyses

BJ Callahan, K Sankaran, JA Fukuyama… - …, 2016 - ncbi.nlm.nih.gov
High-throughput sequencing of PCR-amplified taxonomic markers (like the 16S rRNA gene)
has enabled a new level of analysis of complex bacterial communities known as …

Rhea: a transparent and modular R pipeline for microbial profiling based on 16S rRNA gene amplicons

I Lagkouvardos, S Fischer, N Kumar, T Clavel - PeerJ, 2017 - peerj.com
The importance of 16S rRNA gene amplicon profiles for understanding the influence of
microbes in a variety of environments coupled with the steep reduction in sequencing costs …

Pavian: interactive analysis of metagenomics data for microbiome studies and pathogen identification

FP Breitwieser, SL Salzberg - Bioinformatics, 2020 - academic.oup.com
Pavian is a web application for exploring classification results from metagenomics
experiments. With Pavian, researchers can analyze, visualize and transform results from …

[HTML][HTML] ranacapa: An R package and Shiny web app to explore environmental DNA data with exploratory statistics and interactive visualizations

GS Kandlikar, ZJ Gold, MC Cowen, RS Meyer… - …, 2018 - ncbi.nlm.nih.gov
Environmental DNA (eDNA) metabarcoding is becoming a core tool in ecology and
conservation biology, and is being used in a growing number of education, biodiversity …

Fish skin and gut microbiomes show contrasting signatures of host species and habitat

FÉ Sylvain, A Holland, S Bouslama… - Applied and …, 2020 - Am Soc Microbiol
Teleost fish represent an invaluable repertoire of host species to study the factors shaping
animal-associated microbiomes. Several studies have shown that the phylogenetic structure …

Recent past, present, and future of the food microbiome

F De Filippis, E Parente, D Ercolini - Annual Review of Food …, 2018 - annualreviews.org
Sequencing technologies have deeply changed our approach to the study of food microbial
communities. This review describes recent exploitations of high-throughput sequencing …