Abstract Pharmaceutical three-dimensional (3D) printing is a modern fabrication process
with the potential to create bespoke drug products of virtually any shape and size from a …

Most pharmaceuticals are given using short-acting formulations that require frequent
administration, which can negatively affect patient compliance and increase failure risks …

The minimally-invasive and painless nature of microneedle (MN) application has enabled
the technology to obviate many issues with injectable drug delivery. MNs not only administer …

Non-oral long-acting drug delivery systems (LADDS) encompass a range of technologies for
precisely delivering drug molecules into target tissues either through the systemic circulation …

Precise delivery of therapeutics to the target structures is essential for treatment efficiency
and safety. Drug administration via conventional routes requires overcoming multiple …

Peri-implant fibrosis (PIF) increases the postsurgical risks after implantation and limits the
efficacy of the implantable drug delivery systems (IDDS). Pirfenidone (PF) is an oral anti …

A novel organic–inorganic gliclazide-loaded composite bead was developed by an ionic
gelation process using acidified CaCl2, chitosan and tetraethylorthosilicate (TEOS) as a …

Hot-melt extrusion (HME) has an esteemed place in the pharmaceutical industry with
significant applications and advancements spreading over 30 years of development …

Smart implants continue to evolve, posing tremendous opportunities to move towards
personalized and pervasive healthcare in Sub-Saharan Africa (SSA). However, the adoption …

This study leverages the advantages of two fabrication techniques, namely, melt-extrusion-
based 3D printing and porogen leaching, to develop multiphasic scaffolds with controllable …