The oral microbiome and cancer

M Irfan, RZR Delgado, J Frias-Lopez - Frontiers in immunology, 2020 - frontiersin.org
There is mounting evidence that members of the human microbiome are highly associated
with a wide variety of cancer types. Among oral cancers, oral squamous cell carcinoma …

Fusobacterium nucleatum and oral cancer: a critical review

E McIlvanna, GJ Linden, SG Craig, FT Lundy… - BMC cancer, 2021 - Springer
There is a growing level of interest in the potential role inflammation has on the initiation and
progression of malignancy. Notable examples include Helicobacter pylori-mediated …

The cancer microbiome: recent highlights and knowledge gaps

RJ Knippel, JL Drewes, CL Sears - Cancer discovery, 2021 - AACR
Abstract Knowledge of the human microbiome, which is likely a critical factor in the initiation,
progression, and prognosis of multiple forms of cancer, is rapidly expanding. In this review …

[HTML][HTML] Fusobacterium nucleatum outer membrane vesicles activate autophagy to promote oral cancer metastasis

G Chen, C Gao, S Jiang, Q Cai, R Li, Q Sun… - Journal of Advanced …, 2024 - Elsevier
Introduction Metastasis is an important cause of high mortality and lethality of oral cancer.
Fusobacterium nucleatum (Fn) can promote tumour metastasis. Outer membrane vesicles …

The key differences between human papillomavirus-positive and-negative head and neck cancers: biological and clinical implications

SF Powell, L Vu, WC Spanos, D Pyeon - Cancers, 2021 - mdpi.com
Simple Summary Head and neck cancer (HNC) is the sixth most common cancer, causing
almost half a million deaths worldwide every year. The two subtypes of HNC are distinctly …

Oral microbiome associated with lymph node metastasis in oral squamous cell carcinoma

YG Eun, JW Lee, SW Kim, DW Hyun, JW Bae… - Scientific Reports, 2021 - nature.com
Oral microbiota can alter cancer susceptibility and progression by modulating metabolism
and inflammation. We assessed the association between the oral microbiome and lymph …

Prognostic value of intratumoral Fusobacterium nucleatum and association with immune-related gene expression in oral squamous cell carcinoma patients

C Neuzillet, M Marchais, S Vacher, M Hilmi… - Scientific Reports, 2021 - nature.com
Abstract Changes in the oral microbiome, particularly Fusobacterium nucleatum, are
associated with oral squamous cell carcinoma (OSCC). F. nucleatum has been reported to …

Pathogenic Mechanisms of Fusobacterium nucleatum on Oral Epithelial Cells

S Groeger, Y Zhou, S Ruf, J Meyle - Frontiers in Oral Health, 2022 - frontiersin.org
Periodontitis is an oral chronic inflammatory disease and may cause tooth loss in adults.
Oral epithelial cells provide a barrier for bacteria and participate in the immune response …

Effects of Lacticaseibacillus paracasei SNB-derived postbiotic components on intestinal barrier dysfunction and composition of gut microbiota

L Xiao, C Zhang, X Zhang, X Zhao, GC Mahsa… - Food Research …, 2024 - Elsevier
The bacterial surface components are considered as effector molecules and show the
potential to support intestinal health, but the detailed mechanism of how the gut microbiota …

Oral microbiota from periodontitis promote oral squamous cell carcinoma development via γδ T cell activation

W Wei, J Li, X Shen, J Lyu, C Yan, B Tang, W Ma… - Msystems, 2022 - Am Soc Microbiol
Oral squamous cell carcinoma (OSCC) is a fatal disease, and periodontitis is associated
with OSCC development. However, the pathogenesis in the context of OSCC with …