Glioblastoma multiforme (GBM) is the most common and aggressive malignant primary brain
tumour in humans and has a very poor prognosis. The existing treatments have had limited …

Gastroenteropancreatic (GEP) neuroendocrine neoplasms (NENs) are heterogeneous
regarding site of origin, biological behavior, and malignant potential. There has been a rapid …

N 6-methyladenosine (m6A) has emerged as the most abundant mRNA modification that
regulates gene expression in many physiological processes. m6A modification in RNA …

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces apoptosis
selectively via its interaction with the death receptors TRAILR1/DR4 and TRAILR2/DR5 in a …

Glioblastoma ranks among the most lethal of all human cancers. Glioblastomas display
striking cellular heterogeneity, with stem-like glioblastoma stem cells (GSCs) at the apex …

Glioblastoma multiforme (GBM) is among the most incurable cancers. GBMs survival rate
has not markedly improved, despite new radical surgery protocols, the introduction of new …

Glioblastoma multiforme (GBM) is the most lethal primary brain tumor characterized by high
cellular and molecular heterogeneity, hypervascularization, and innate drug resistance …

DAXX displays complex biological functions. Remarkably, DAXX overexpression is a
common feature in diverse cancers, which correlates with tumorigenesis, disease …

Background E2F transcription factors are considered to be important drivers of tumour
growth. E2F7 is an atypical E2F factor, and its role in glioblastoma remains undefined …

Abstract Circular RNAs (CircRNAs) are non-coding RNAs (ncRNAs) characterized by a
stable circular structure that regulates gene expression at both transcriptional and post …