Update on the pathomechanism, diagnosis, and treatment options for rheumatoid arthritis
YJ Lin, M Anzaghe, S Schülke - Cells, 2020 - mdpi.com
Rheumatoid arthritis (RA) is an autoimmune disease that involves multiple joints bilaterally.
It is characterized by an inflammation of the tendon (tenosynovitis) resulting in both cartilage …
It is characterized by an inflammation of the tendon (tenosynovitis) resulting in both cartilage …
Genetic susceptibility to rheumatoid arthritis: an emerging picture
A Barton, J Worthington - Arthritis Care & Research, 2009 - research.manchester.ac.uk
At least 13 loci have now been confidently confirmed as being associated with RA
susceptibility, and further insights into the genetic contribution to disease are likely to be …
susceptibility, and further insights into the genetic contribution to disease are likely to be …
Meta-analysis reveals an association of PTPN22 C1858T with autoimmune diseases, which depends on the localization of the affected tissue
Protein tyrosine phosphatase non-receptor type 22 (PTPN22) is a strong susceptibility gene
shared by many autoimmune diseases. The aim of this study was to explore the …
shared by many autoimmune diseases. The aim of this study was to explore the …
PTPN22 gene polymorphism and susceptibility to rheumatoid arthritis (RA): Updated systematic review and meta‐analysis
M Abbasifard, D Imani… - The journal of gene …, 2020 - Wiley Online Library
Background Several genome‐wide association studies have revealed a genetic background
with respect to susceptibility to rheumatoid arthritis (RA). Although several individual case …
with respect to susceptibility to rheumatoid arthritis (RA). Although several individual case …
Meta-analysis reveals PTPN22 1858C/T polymorphism confers susceptibility to rheumatoid arthritis in Caucasian but not in Asian population
Abstract The PTPN22 1858C/T polymorphism is associated with rheumatoid arthritis (RA).
However, reports from the Asian populations are conflicting in nature and lacks consensus …
However, reports from the Asian populations are conflicting in nature and lacks consensus …
Triggers and regulation: the gut microbiome in rheumatoid arthritis
Introduction Rheumatoid arthritis is a chronic inflammatory disease marked by systemic
symptoms and joint degeneration. Interestingly, the development and progression of …
symptoms and joint degeneration. Interestingly, the development and progression of …
Association of PTPN22 rs2476601 and STAT4 rs7574865 polymorphisms with rheumatoid arthritis: A meta-analysis update
R Elshazli, A Settin - Immunobiology, 2015 - Elsevier
Background Rheumatoid arthritis (RA) is a common autoimmune disease with a complex
genetic background. The genes encoding protein tyrosine phosphatase non-receptor type …
genetic background. The genes encoding protein tyrosine phosphatase non-receptor type …
PTPN22 1858C>T Polymorphism Distribution in Europe and Association with Rheumatoid Arthritis: Case-Control Study and Meta-Analysis
MC Totaro, B Tolusso, V Napolioni, F Faustini… - PLoS …, 2011 - journals.plos.org
Objective The PTPN22 rs2476601 polymorphism is associated with rheumatoid arthritis
(RA); nonetheless, the association is weaker or absent in some southern European …
(RA); nonetheless, the association is weaker or absent in some southern European …
The+ 1858C/T PTPN22 gene polymorphism confers genetic susceptibility to rheumatoid arthritis in Mexican population from the Western Mexico
NM Torres-Carrillo, Y Ruiz-Noa, GE Martínez-Bonilla… - Immunology letters, 2012 - Elsevier
INTRODUCTION: Rheumatoid arthritis (RA) is a common autoimmune disease with a
complex genetic background. The PTPN22 gene encodes lymphoid tyrosine phosphatase …
complex genetic background. The PTPN22 gene encodes lymphoid tyrosine phosphatase …
PTPN22 polymorphism presumably plays a role in the genetic background of chronic spontaneous autoreactive urticaria
Z Brzoza, W Grzeszczak, B Rogala, W Trautsolt… - Dermatology, 2012 - karger.com
Background: The association of chronic urticaria (CU) with autoimmune disorders is
relatively well proved. Protein tyrosine phosphatase-22 (PTPN22) is considered to be one of …
relatively well proved. Protein tyrosine phosphatase-22 (PTPN22) is considered to be one of …