Study Design. Literature review. Objective. To evaluate the association between
recombinant human bone morphogenetic protein-2 (rhBMP-2) and malignancy. Summary of …

Bone metastasis is a major cause of morbidity within solid tumours of the breast, prostate,
lung and kidney. Metastasis to the skeleton is associated with a wide range of complications …

Bone metastasis is a frequent occurrence in prostate cancer (PCa) that is associated with
severe complications such as fracture, bone pain and hypercalcemia. The cross-talk …

Concern regarding safety with respect to the clinical use of human bone morphogenetic
protein-2 (BMP-2) has become an increasingly controversial topic. The role of BMP-2 in …

BACKGROUND Approximately 90% of patients who die of Prostate Cancer (PCa) have
bone metastases, which promote a spectrum of osteoblastic, osteolytic or mixed bone …

In addition to its well-known role as an energy repository, adipose tissue is one of the largest
endocrine organs in the organism due to its ability to synthesize and release different …

The main aim of this study was to investigate the putative association among the presence of
prostate cancer cells, defined as prostate osteoblast‐like cells (POLCs), and showing the …

Bone morphogenetic protein receptor 2 (BMPR2) has been identified in several types of
cancer. However, its role in osteosarcoma is largely unknown. We systematically …

Prostate cancer is the second most frequently diagnosed cancer worldwide and is the sixth
leading cause of cancer deaths in men, yet it varies greatly in its aggressiveness. Currently …

Androgens are a major driver of prostate cancer (PCa) and continue to be a critical treatment
target for advanced disease, which includes castration therapy and antiandrogens …