In recent years, the number and types of known functional noncoding RNAs have increased
considerably. A subset of both short-and long-sized species are known to be involved in the …

With rapid development of sequencing technologies such as deep sequencing and whole
genome high-density tiling array, we now know that most of the “junk” genomic sequences …

Alternative splicing is a post-transcriptional regulatory mechanism producing distinct mRNA
molecules from a single pre-mRNA with a prominent role in the development and function of …

Background Drought is the major constraint to increase yield in chickpea (Cicer arietinum).
Improving drought tolerance is therefore of outmost importance for breeding. However, the …

Epigenetics refers to chromatin-based pathways important in the regulation of gene
expression and includes 3 distinct, but highly interrelated, mechanisms: DNA methylation …

Comprehensive analysis of the mammalian transcriptome has revealed that long non-
coding RNAs (lncRNAs) may make up a large fraction of cellular transcripts. Recent years …

Retroelements comprise a considerable fraction of eukaryotic genomes. Since their initial
discovery by Barbara McClintock in maize DNA, retroelements have been found in genomes …

Cell surface proteins are excellent targets for diagnostic and therapeutic interventions. By
using bioinformatics tools, we generated a catalog of 3,702 transmembrane proteins located …

The era of whole-genome sequencing has revealed that gene copy-number changes
caused by duplication and deletion events have important evolutionary, functional, and …

Background In spite of large intergenic spaces in plant and animal genomes, 7% to 30% of
genes in the genomes encode overlapping cis-natural antisense transcripts (cis-NATs). The …