Epstein–Barr virus (EBV) is the first identified human oncogenic virus that can establish asymptomatic life-long persistence. It is associated with a large spectrum of diseases …
Epstein-Barr virus (EBV) causes Burkitt, Hodgkin, and post-transplant B cell lymphomas. How EBV remodels metabolic pathways to support rapid B cell outgrowth remains largely …
WH Robinson, S Younis, ZZ Love, L Steinman… - Nature Reviews …, 2024 - nature.com
Abstract The Epstein–Barr virus (EBV) is epidemiologically associated with development of autoimmune diseases, including systemic lupus erythematosus, Sjögren syndrome …
H Zhou, SCS Schmidt, S Jiang, B Willox, K Bernhardt… - Cell host & …, 2015 - cell.com
Super-enhancers are clusters of gene-regulatory sites bound by multiple transcription factors that govern cell transcription, development, phenotype, and oncogenesis. By …
Epstein-Barr virus (EBV) is a ubiquitous gammaherpesvirus which asymptomatically infects the majority of the world population. Under immunocompromised conditions, EBV can …
B Zhao, J Zou, H Wang, E Johannsen… - Proceedings of the …, 2011 - National Acad Sciences
Epstein-Barr virus nuclear antigen 2 (EBNA2) regulation of transcription through the cell transcription factor RBPJ is essential for resting B-lymphocyte (RBL) conversion to immortal …
I Wierstra, J Alves - Advances in cancer research, 2008 - Elsevier
The transcription factor c‐Myc is a key regulator of cell proliferation, cell growth, differentiation, and apoptosis. Deregulated c‐myc expression possesses a high …
S Jiang, H Zhou, J Liang, C Gerdt, C Wang, L Ke… - Cell host & …, 2017 - cell.com
Epstein-Barr virus (EBV) transforms B cells to continuously proliferating lymphoblastoid cell lines (LCLs), which represent an experimental model for EBV-associated cancers. EBV …
C Wang, D Li, L Zhang, S Jiang, J Liang… - Journal of …, 2019 - Am Soc Microbiol
Epstein-Barr virus (EBV) infection of human primary resting B lymphocytes (RBLs) leads to the establishment of lymphoblastoid cell lines (LCLs) that can grow indefinitely in vitro. EBV …