The complex aetiology of cerebral palsy

SJ Korzeniewski, J Slaughter, M Lenski… - Nature Reviews …, 2018 - nature.com
Cerebral palsy (CP) is the most prevalent, severe and costly motor disability of childhood.
Consequently, CP is a public health priority for prevention, but its aetiology has proved …

Diagnosis and surveillance of late-onset fetal growth restriction

F Figueras, J Caradeux, F Crispi, E Eixarch… - American journal of …, 2018 - Elsevier
By consensus, late fetal growth restriction is that diagnosed> 32 weeks. This condition is
mildly associated with a higher risk of perinatal hypoxic events and suboptimal …

The placental basis of fetal growth restriction

RL Zur, WT Parks, SR Hobson - Obstetrics and Gynecology …, 2020 - obgyn.theclinics.com
The past decade has seen a substantial advancement in our understanding of placental
diseases that are associated with fetal growth restriction (FGR). 1 This increased …

Screening for fetal growth restriction and placental insufficiency

MC Audette, JC Kingdom - Seminars in Fetal and Neonatal Medicine, 2018 - Elsevier
Fetal growth restriction (FGR) continues to be a leading cause of preventable stillbirth and
poor neurodevelopmental outcomes in offspring, and furthermore is strongly associated with …

Metformin, the aspirin of the 21st century: its role in gestational diabetes mellitus, prevention of preeclampsia and cancer, and the promotion of longevity

R Romero, O Erez, M Hüttemann, E Maymon… - American journal of …, 2017 - Elsevier
Metformin is everywhere. Originally introduced in clinical practice as an antidiabetic agent,
its role as a therapeutic agent is expanding to include treatment of prediabetes mellitus …

[HTML][HTML] Toward a new taxonomy of obstetrical disease: improved performance of maternal blood biomarkers for the great obstetrical syndromes when classified …

R Romero, E Jung, T Chaiworapongsa, O Erez… - American journal of …, 2022 - Elsevier
Background The major challenge for obstetrics is the prediction and prevention of the great
obstetrical syndromes. We propose that defining obstetrical diseases by the combination of …

Failure of physiologic transformation of spiral arteries, endothelial and trophoblast cell activation, and acute atherosis in the basal plate of the placenta

CA Labarrere, HL DiCarlo, E Bammerlin… - American journal of …, 2017 - Elsevier
Background Failure of physiologic transformation of spiral arteries has been reported in
preeclampsia, fetal growth restriction, fetal death, and spontaneous preterm labor with intact …

Screening for fetal growth restriction using ultrasound and the sFLT1/PlGF ratio in nulliparous women: a prospective cohort study

F Gaccioli, U Sovio, E Cook, M Hund… - The Lancet Child & …, 2018 - thelancet.com
Background Fetal growth restriction is a major determinant of perinatal morbidity and
mortality. This condition has no gold standard definition, but a widely used proxy is delivery …

The prediction of early preeclampsia: Results from a longitudinal proteomics study

AL Tarca, R Romero, N Benshalom-Tirosh, NG Than… - PloS one, 2019 - journals.plos.org
Objectives To identify maternal plasma protein markers for early preeclampsia (delivery< 34
weeks of gestation) and to determine whether the prediction performance is affected by …

Bronchopulmonary Dysplasia–Associated Pulmonary Hypertension: An Updated Review

A El-Saie, NP Varghese, MK Webb, N Villafranco… - Seminars in …, 2023 - Elsevier
Bronchopulmonary dysplasia (BPD) is the leading cause of chronic lung disease in infants
and the commonest complication of prematurity. Advances in respiratory and overall …