The commensal lifestyle of Staphylococcus aureus and its interactions with the nasal microbiota

B Krismer, C Weidenmaier, A Zipperer… - Nature reviews …, 2017 - nature.com
Although human colonization by facultative bacterial pathogens, such as Staphylococcus
aureus, represents a major risk factor for invasive infections, the commensal lifestyle of such …

Phage-mediated horizontal gene transfer and its implications for the human gut microbiome

T Borodovich, AN Shkoporov, RP Ross… - Gastroenterology …, 2022 - academic.oup.com
Horizontal gene transfer (HGT) in the microbiome has profound consequences for human
health and disease. The spread of antibiotic resistance genes, virulence, and pathogenicity …

Transfer of antibiotic resistance in Staphylococcus aureus

J Haaber, JR Penadés, H Ingmer - Trends in microbiology, 2017 - cell.com
Staphylococcus aureus is a serious human pathogen with remarkable adaptive powers.
Antibiotic-resistant clones rapidly emerge mainly by acquisition of antibiotic-resistance …

Bacterial viruses enable their host to acquire antibiotic resistance genes from neighbouring cells

J Haaber, JJ Leisner, MT Cohn… - Nature …, 2016 - nature.com
Prophages are quiescent viruses located in the chromosomes of bacteria. In the human
pathogen, Staphylococcus aureus, prophages are omnipresent and are believed to be …

β-Lactams against the Fortress of the Gram-Positive Staphylococcus aureus Bacterium

JF Fisher, S Mobashery - Chemical reviews, 2020 - ACS Publications
The biological diversity of the unicellular bacteria—whether assessed by shape, food,
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …

Genetic engineering of a temperate phage-based delivery system for CRISPR/Cas9 antimicrobials against Staphylococcus aureus

JY Park, BY Moon, JW Park, JA Thornton, YH Park… - Scientific reports, 2017 - nature.com
Discovery of clustered, regularly interspaced, short palindromic repeats and the Cas9 RNA-
guided nuclease (CRISPR/Cas9) system provides a new opportunity to create …

Bacterial Targets of Antibiotics in Methicillin-Resistant Staphylococcus aureus

H Lade, JS Kim - Antibiotics, 2021 - mdpi.com
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most prevalent bacterial
pathogens and continues to be a leading cause of morbidity and mortality worldwide. MRSA …

Bacterial glycobiology: rhamnose-containing cell wall polysaccharides in Gram-positive bacteria

MY Mistou, IC Sutcliffe… - FEMS microbiology …, 2016 - academic.oup.com
The composition of the Gram-positive cell wall is typically described as containing
peptidoglycan, proteins and essential secondary cell wall structures called teichoic acids …

Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity

D Gerlach, Y Guo, C De Castro, SH Kim, K Schlatterer… - Nature, 2018 - nature.com
Methicillin-resistant Staphylococcus aureus (MRSA) is a frequent cause of difficult-to-treat,
often fatal infections in humans,. Most humans have antibodies against S. aureus, but these …

Staphylococcus aureus genomics and the impact of horizontal gene transfer

JA Lindsay - International Journal of Medical Microbiology, 2014 - Elsevier
Whole genome sequencing and microarrays have revealed the population structure of
Staphylococcus aureus, and identified epidemiological shifts, transmission routes, and …