The neuropsychology of Huntington's disease

JS Snowden - Archives of Clinical Neuropsychology, 2017 - academic.oup.com
Huntington's disease is an inherited, degenerative brain disease, characterized by
involuntary movements, cognitive disorder and neuropsychiatric change. Men and women …

Multiple clinical features of Huntington's disease correlate with mutant HTT gene CAG repeat lengths and neurodegeneration

S Podvin, HT Reardon, K Yin, C Mosier, V Hook - Journal of neurology, 2019 - Springer
Huntington's disease (HD) is a fatal neurodegenerative disease caused by mutant HTT gene
expansions of CAG triplet repeat numbers that are inherited in an autosomal dominant …

Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease

I Arnoux, M Willam, N Griesche, J Krummeich, H Watari… - elife, 2018 - elifesciences.org
Catching primal functional changes in early,'very far from disease onset'(VFDO) stages of
Huntington's disease is likely to be the key to a successful therapy. Focusing on VFDO …

[HTML][HTML] Resting-state fMRI reveals longitudinal alterations in brain network connectivity in the zQ175DN mouse model of Huntington's disease

T Vasilkovska, MH Adhikari, J Van Audekerke… - Neurobiology of …, 2023 - Elsevier
Huntington's disease is an autosomal, dominantly inherited neurodegenerative disease
caused by an expansion of the CAG repeats in exon 1 of the huntingtin gene. Neuronal …

Mild cognitive impairment and dementia in motor manifest Huntington's disease: classification and prevalence

P Julayanont, NR McFarland, KM Heilman - Journal of the neurological …, 2020 - Elsevier
Objectives To identify the characteristics and prevalence of mild cognitive impairment in
patients with motor-manifest Huntington's disease (HD) and to propose a new mild cognitive …

[HTML][HTML] Huntington's disease mouse models: Unraveling the pathology caused by CAG repeat expansion

J Kaye, T Reisine, S Finkbeiner - Faculty reviews, 2021 - ncbi.nlm.nih.gov
Huntington's disease (HD) is a neurodegenerative disease that results in motor and
cognitive dysfunction, leading to early death. HD is caused by an expansion of CAG repeats …

Dynamic functional network connectivity in Huntington's disease and its associations with motor and cognitive measures

FA Espinoza, J Liu, J Ciarochi, JA Turner… - Human brain …, 2019 - Wiley Online Library
Dynamic functional network connectivity (dFNC) is an expansion of traditional, static FNC
that measures connectivity variation among brain networks throughout scan duration. We …

[HTML][HTML] Huntington's disease patients display progressive deficits in hippocampal-dependent cognition during a task of spatial memory

KL Harris, M Armstrong, R Swain, S Erzinclioglu, T Das… - Cortex, 2019 - Elsevier
Background Cognitive disturbances occur early in Huntington's disease (HD) and place a
significant burden on the lives of patients and family members. Whilst these impairments are …

Structural and functional changes of the visual cortex in early Huntington's disease

EM Coppen, J Grond, A Hafkemeijer… - Human brain …, 2018 - Wiley Online Library
Huntington's disease (HD) is an autosomal‐dominant inherited neurodegenerative disorder
characterized by motor disturbances, psychiatric disturbances, and cognitive impairment …

Neural correlates of cognitive impairment in Parkinson's disease: a review of structural MRI findings

JM Hall, SJG Lewis - International review of neurobiology, 2019 - Elsevier
Cognitive impairment is one of the most salient non-motor symptoms of Parkinson's disease
(PD). Cognitive decline poses a significant burden on the patient as well as the caregiver …