The emergence of new pathogens and multidrug resistant bacteria is an important public
health issue that requires the development of novel classes of antibiotics. Antimicrobial …

Granular glands in the skins of frogs of the genus Rana, a widely distributed group with over
250 species, synthesize and secrete a remarkably diverse array of peptides with …

The COVID-19 pandemic has evidenced the urgent need for the discovery of broad-
spectrum antiviral therapies that could be deployed in the case of future emergence of novel …

The rising prevalence of antibiotic resistance underscores the urgent need for novel
antimicrobial agents. Antimicrobial peptides (AMPs) are potentially effective therapeutics …

Invasive fungal infections are associated with high mortality rates, despite appropriate
antifungal therapy. Limited therapeutic options, resistance development and the high …

Antimicrobial Peptides (AMPs) are one of the most common components of the innate
immune system that protect multicellular organisms against microbial invasion. The vast …

More than a thousand antimicrobial peptides (AMPs) have been reported in the last decades
arising from the skin secretion of amphibian species. Generally, each frog species can …

Leishmaniasis encompasses a wide range of infections caused by the human parasitic
protozoan species belonging to the Leishmania genus. It appears frequently as an …

The temporins are a family of small, linear antibiotic peptides with intriguing biological
properties. We investigated the antibacterial, haemolytic and cytotoxic activities of temporin …

The high-resolution three-dimensional structure of an antimicrobial peptide has implications
for the mechanism of its antimicrobial activity, as the conformation of the peptide provides …