Radiosynthesis, preclinical, and clinical positron emission tomography studies of carbon-11 labeled endogenous and natural exogenous compounds

A Shegani, S Kealey, F Luzi, F Basagni… - Chemical …, 2022 - ACS Publications
The presence of positron emission tomography (PET) centers at most major hospitals
worldwide, along with the improvement of PET scanner sensitivity and the introduction of …

Recent developments in carbon-11 chemistry and applications for first-in-human PET studies

A Pees, M Chassé, A Lindberg, N Vasdev - Molecules, 2023 - mdpi.com
Positron emission tomography (PET) is a molecular imaging technique that makes use of
radiolabelled molecules for in vivo evaluation. Carbon-11 is a frequently used radionuclide …

[HTML][HTML] 11C-Para-aminobenzoic acid PET imaging of S. aureus and MRSA infection in preclinical models and humans

AA Ordonez, MFL Parker, RJ Miller, D Plyku… - JCI insight, 2022 - ncbi.nlm.nih.gov
Tools for noninvasive detection of bacterial pathogens are needed but are not currently
available for clinical use. We have previously shown that para-aminobenzoic acid (PABA) …

[HTML][HTML] SPECT and PET radiotracers in renal imaging

RA Werner, MG Pomper, AK Buck, SP Rowe… - Seminars in Nuclear …, 2022 - Elsevier
Diuretic scintigraphy includes single-photon emitting radiotracers for planar and single
photon emission computed tomography (SPECT) imaging as well as agents for positron …

[HTML][HTML] Current and future perspectives on functional molecular imaging in nephro-urology: theranostics on the horizon

Y Toyama, RA Werner, CA Ruiz-Bedoya… - Theranostics, 2021 - ncbi.nlm.nih.gov
In recent years, a paradigm shift from single-photon-emitting radionuclide radiotracers
toward positron-emission tomography (PET) radiotracers has occurred in nuclear oncology …

Neural KEM: A kernel method with deep coefficient prior for PET image reconstruction

S Li, K Gong, RD Badawi, EJ Kim, J Qi… - IEEE transactions on …, 2022 - ieeexplore.ieee.org
Image reconstruction of low-count positron emission tomography (PET) data is challenging.
Kernel methods address the challenge by incorporating image prior information in the …

The utilization of positron emission tomography in the evaluation of renal health and disease

KA Amoabeng, S Laurila, LE Juárez-Orozco… - Clinical and …, 2022 - Springer
Purpose Positron emission tomography (PET) is a nuclear imaging technique that uses
radiotracers to visualize metabolic processes of interest across different organs, to diagnose …

2-[18F]F-p-Aminobenzoic Acid Specifically Detects Infective Endocarditis in Positron Emission Tomography

J Schulte, A Maurer, LC Domogalla… - The Journal of …, 2024 - academic.oup.com
Background Infective endocarditis (IE) is a life-threatening disease with high mortality,
particularly when caused by Staphylococcus aureus (S aureus). Traditional diagnosis relies …

PET/CT Imaging of Infectious Diseases: Overview of Novel Radiopharmaceuticals

FF Calabria, G Guadagnino, A Cimini, M Leporace - Diagnostics, 2024 - mdpi.com
Infectious diseases represent one of the most common causes of hospital admission
worldwide. The diagnostic work-up requires a complex clinical approach, including …

Role of Functional SPECT and PET in Renal Emergencies

T Higuchi, PE Hartrampf, AK Buck, MG Pomper… - Seminars in Nuclear …, 2023 - Elsevier
Renal scintigraphy is a centerpiece of nuclear medicine and is also commonly applied for
(peri-) acute care. In this regard, referrals by the treating physician include: I.) acute …