Fast-spiking (FS) interneurons in the brain are self-innervated by powerful inhibitory
GABAergic autaptic connections. By computational modelling, we investigate how autaptic …

Complex dendrites in general present formidable challenges to understanding neuronal
information processing. To circumvent the difficulty, a prevalent viewpoint simplifies the …

Background: Type 2 diabetes mellitus (T2DM) is a worldwide socioeconomic burden, and is
accompanied by a variety of metabolic disorders, as well as nerve dysfunction referred to as …

Neurons, represented as a tree structure of morphology, have various distinguished
branches of dendrites. Different types of synaptic receptors distributed over dendrites are …

Neurons compute by integrating spatiotemporal excitatory (E) and inhibitory (I) synaptic
inputs received from the dendrites. The investigation of dendritic integration is crucial for …

Synaptic transmission between neurons is the basic unit of communication in neural circuits.
The relative number and distribution of excitatory and inhibitory synaptic inputs across …

The core of multimodal sentiment analysis is to find effective encoding and fusion methods
to make accurate predictions. However, previous works ignore the problems caused by the …

Interneurons are important for computation in the brain, in particular, in the information
processing involving the generation of theta oscillations in the hippocampus. Yet the …

Differing from other subtypes of inhibitory interneuron, chandelier or axo-axonic cells form
depolarizing GABAergic synapses exclusively onto the axon initial segment (AIS) of targeted …

The interplay between excitatory and inhibitory neurons imparts rich functions of the brain.
To understand the synaptic mechanisms underlying neuronal computations, a fundamental …