Widely used types and clinical applications of D-dimer assay

RS Riley, AR Gilbert, JB Dalton, S Pai… - Laboratory …, 2016 - academic.oup.com
ABSTRACT D-dimers are formed by the breakdown of fibrinogen and fibrin during
fibrinolysis. D-dimer analysis is critical for the diagnosis of deep vein thrombosis, pulmonary …

Biomarkers for prediction of venous thromboembolism in cancer

I Pabinger, J Thaler, C Ay - Blood, The Journal of the American …, 2013 - ashpublications.org
Cancer patients are at increased risk of deep vein thrombosis and pulmonary embolism. The
incidence among different groups of cancer patients varies considerably depending on …

D-dimer level is a useful predictor for mortality in patients with COVID-19: Analysis of 483 cases

M Soni, R Gopalakrishnan, R Vaishya… - Diabetes & Metabolic …, 2020 - Elsevier
Background and aims COVID-19 is a multi-system disease, with coagulation abnormalities.
D-dimer levels are increased in this disease. We aimed to determine the association of D …

A clinical prediction model for cancer-associated venous thromboembolism: a development and validation study in two independent prospective cohorts

I Pabinger, N van Es, G Heinze, F Posch… - The Lancet …, 2018 - thelancet.com
Background Venous thromboembolism is a common complication of cancer, but the risk of
developing venous thromboembolism varies greatly among individuals and depends on …

D-dimer predicts long-term cause-specific mortality, cardiovascular events, and cancer in patients with stable coronary heart disease: LIPID study

J Simes, KP Robledo, HD White, D Espinoza… - Circulation, 2018 - Am Heart Assoc
Background: D-dimer, a degradation product of cross-linked fibrin, is a marker for
hypercoagulability and thrombotic events. Moderately elevated levels of D-dimer are …

Coagulation and fibrinolysis in gastric cancer

O Repetto, V De Re - Annals of the New York Academy of …, 2017 - Wiley Online Library
Coagulation is a highly conserved process occurring after an injury to a blood vessel and
resulting in hemostasis. In the thrombus microenvironment, finely orchestrated events …

d-Dimer elevation and adverse outcomes

R Halaby, CJ Popma, A Cohen, G Chi… - Journal of thrombosis …, 2015 - Springer
Abstract d-Dimer is a biomarker of fibrin formation and degradation. While a d-dimer within
normal limits is used to rule out the diagnosis of deep venous thrombosis and pulmonary …

The mortality rate of COVID-19 was high in cancer patients: a retrospective single-center study

GS Erdal, O Polat, GU Erdem, R Korkusuz… - International Journal of …, 2021 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) has quickly turned into a global
pandemic with close to 5 million cases and more than 320,000 deaths. Cancer patients …

[HTML][HTML] Biomarkers for the detection of apparent and subclinical cancer therapy-related cardiotoxicity

L Michel, T Rassaf, M Totzeck - Journal of thoracic disease, 2018 - ncbi.nlm.nih.gov
Progress in cancer therapy over the past decades improved long-term survival but increased
cancer therapy-related cardiotoxicity. Many novel treatment options have been implemented …

Impact of fibrinogen, fibrin thrombi, and thrombin on cancer cell extravasation using in vitro microvascular networks

E Angelidakis, S Chen, S Zhang, Z Wan… - Advanced …, 2023 - Wiley Online Library
A bidirectional association exists between metastatic dissemination and the
hypercoagulable state associated with many types of cancer. As such, clinical studies have …