Research Review: A guide to computing and implementing polygenic scores in developmental research

AG Allegrini, JR Baldwin, W Barkhuizen… - Journal of Child …, 2022 - Wiley Online Library
The increasing availability of genotype data in longitudinal population‐and family‐based
samples provides opportunities for using polygenic scores (PGS) to study developmental …

Causal inference methods for intergenerational research using observational data.

L Frach, ES Jami, TA McAdams, F Dudbridge… - Psychological …, 2023 - psycnet.apa.org
Identifying early causal factors leading to the development of poor mental health and
behavioral outcomes is essential to design efficient preventive interventions. The substantial …

A genetically informed Registered Report on adverse childhood experiences and mental health

JR Baldwin, HM Sallis, T Schoeler, MJ Taylor… - Nature human …, 2023 - nature.com
Children who experience adversities have an elevated risk of mental health problems.
However, the extent to which adverse childhood experiences (ACEs) cause mental health …

[HTML][HTML] The next 10 years of behavioural genomic research

R Plomin - JCPP advances, 2022 - ncbi.nlm.nih.gov
Background The explosion caused by the fusion of quantitative genetics and molecular
genetics will transform behavioural genetic research in child and adolescent psychology …

Subjective and objective experiences of childhood adversity: a meta‐analysis of their agreement and relationships with psychopathology

ER Francis, A Tsaligopoulou, SE Stock… - Journal of child …, 2023 - Wiley Online Library
Background Researchers use both subjective self‐report and objective measures, such as
official records, to investigate the impact of childhood adversity on psychopathology …

Commentary: Will genomics revolutionise research on gene–environment interplay?

R Plomin, E Viding - Journal of Child Psychology and …, 2022 - Wiley Online Library
The synthesis of quantitative genetics and molecular genetics is transforming research in the
behavioural sciences. The ability to measure inherited DNA differences directly has led to …

[HTML][HTML] Examining intergenerational risk factors for conduct problems using polygenic scores in the Norwegian Mother, Father and Child Cohort Study

L Frach, W Barkhuizen, AG Allegrini, H Ask… - Molecular …, 2024 - nature.com
The aetiology of conduct problems involves a combination of genetic and environmental
factors, many of which are inherently linked to parental characteristics given parents' central …

Shared Genetic Risk in the Association of Screen Time With Psychiatric Problems in Children

Y Zhang, KW Choi, SW Delaney, T Ge… - JAMA Network …, 2023 - jamanetwork.com
Importance Children's exposure to screen time has been associated with poor mental health
outcomes, yet the role of genetic factors remains largely unknown. Objective To assess the …

Does the polygenic revolution herald a watershed in the study of GE interplay in developmental psychopathology? Some considerations for the Special Issue reader

ED Barker, B Maughan, A Allegrini… - Journal of Child …, 2022 - Wiley Online Library
The primary goal motivating the scientific field of Developmental Psychopathology is to
discover why some individuals develop mental health and neuro‐developmental difficulties …

Mapping potential pathways from polygenic liability through brain structure to psychological problems across the transition to adolescence

BB Lahey, EL Durham, SJ Brislin… - Journal of Child …, 2024 - Wiley Online Library
Background We used a polygenic score for externalizing behavior (extPGS) and structural
MRI to examine potential pathways from genetic liability to conduct problems via the brain …