Rising to the challenge: accelerated pace of discovery transforms marine virology

JR Brum, MB Sullivan - Nature Reviews Microbiology, 2015 - nature.com
Marine viruses have important roles in microbial mortality, gene transfer, metabolic
reprogramming and biogeochemical cycling. In this Review, we discuss recent technological …

Integrating viral metagenomics into an ecological framework

P Sommers, A Chatterjee, A Varsani… - Annual review of …, 2021 - annualreviews.org
Viral metagenomics has expanded our knowledge of the ecology of uncultured viruses,
within both environmental (eg, terrestrial and aquatic) and host-associated (eg, plants and …

Rapid evolutionary turnover of mobile genetic elements drives bacterial resistance to phages

FA Hussain, J Dubert, J Elsherbini, M Murphy… - Science, 2021 - science.org
Although it is generally accepted that phages drive bacterial evolution, how these dynamics
play out in the wild remains poorly understood. We found that susceptibility to viral killing in …

Global trends in marine plankton diversity across kingdoms of life

FM Ibarbalz, N Henry, MC Brandão, S Martini… - Cell, 2019 - cell.com
The ocean is home to myriad small planktonic organisms that underpin the functioning of
marine ecosystems. However, their spatial patterns of diversity and the underlying drivers …

Ecogenomics and potential biogeochemical impacts of globally abundant ocean viruses

S Roux, JR Brum, BE Dutilh, S Sunagawa… - Nature, 2016 - nature.com
Ocean microbes drive biogeochemical cycling on a global scale. However, this cycling is
constrained by viruses that affect community composition, metabolic activity, and …

Patterns and ecological drivers of ocean viral communities

JR Brum, JC Ignacio-Espinoza, S Roux, G Doulcier… - Science, 2015 - science.org
Viruses influence ecosystems by modulating microbial population size, diversity, metabolic
outputs, and gene flow. Here, we use quantitative double-stranded DNA (dsDNA) viral …

Viromes outperform total metagenomes in revealing the spatiotemporal patterns of agricultural soil viral communities

C Santos-Medellin, LA Zinke, AM Ter Horst… - The ISME …, 2021 - academic.oup.com
Viruses are abundant yet understudied members of soil environments that influence
terrestrial biogeochemical cycles. Here, we characterized the dsDNA viral diversity in …

Prokaryotic viruses impact functional microorganisms in nutrient removal and carbon cycle in wastewater treatment plants

Y Chen, Y Wang, D Paez-Espino, MF Polz… - Nature …, 2021 - nature.com
As one of the largest biotechnological applications, activated sludge (AS) systems in
wastewater treatment plants (WWTPs) harbor enormous viruses, with 10-1,000-fold higher …

Freshwater viral metagenome reveals novel and functional phage-borne antibiotic resistance genes

K Moon, JH Jeon, I Kang, KS Park, K Lee, CJ Cha… - Microbiome, 2020 - Springer
Background Antibiotic resistance developed by bacteria is a significant threat to global
health. Antibiotic resistance genes (ARGs) spread across different bacterial populations …

Resolving the structure of phage–bacteria interactions in the context of natural diversity

KM Kauffman, WK Chang, JM Brown… - Nature …, 2022 - nature.com
Microbial communities are shaped by viral predators. Yet, resolving which viruses (phages)
and bacteria are interacting is a major challenge in the context of natural levels of microbial …