Synthesis of 11C, 18F, 15O, and 13N Radiolabels for Positron Emission Tomography

PW Miller, NJ Long, R Vilar… - Angewandte Chemie …, 2008 - Wiley Online Library
Positron emission tomography (PET) is a powerful and rapidly developing area of molecular
imaging that is used to study and visualize human physiology by the detection of positron …

Chemistry with [18F]Fluoride Ion

L Cai, S Lu, VW Pike - European Journal of Organic Chemistry, 2008 - Wiley Online Library
The success of molecular imaging with positron‐emission tomography (PET) depends on
the availability of selective molecular probes labeled with positron‐emitters, such asfluorine …

New method of fluorination using potassium fluoride in ionic liquid: Significantly enhanced reactivity of fluoride and improved selectivity

DW Kim, CE Song, DY Chi - journal of the american chemical …, 2002 - ACS Publications
We have found the new nucleophilic fluorination reaction of some halo-and mesylalkanes to
the corresponding fluoroalkanes with KF in the presence of [bmim][BF4] under various …

Significantly enhanced reactivities of the nucleophilic substitution reactions in ionic liquid

DW Kim, CE Song, DY Chi - The Journal of Organic Chemistry, 2003 - ACS Publications
We have investigated the reactivities of various metal fluorides in the nucleophilic
fluorination of 2-(3-methanesulfonyloxypropyl) naphthalene (1) as a model compound in the …

The combination of hydrogen fluoride with organic bases as fluorination agents

N Yoneda - Tetrahedron, 1991 - Elsevier
In view of the rapidly growing role of organo-fluorine compounds. particularly in material and
pharmaceutical science, the synthesis of organo-fluorine compounds is becoming …

Recent developments and trends in 18F-radiochemistry: syntheses and applications

R Schirrmacher, C Wangler… - Mini-Reviews in …, 2007 - ingentaconnect.com
In this short review we describe recent methods and novel trends for the introduction of
fluorine-18 into molecules which in turn are intended to serve as imaging agents for the in …

Synthese von 11C‐, 18F‐, 15O‐und 13N‐Radiotracern für die Positronenemissionstomographie

PW Miller, NJ Long, R Vilar, AD Gee - Angewandte Chemie, 2008 - Wiley Online Library
Die Positronenemissionstomographie (PET) ist eine leistungsfähige Bildgebungsmethode,
die zur Untersuchung und Visualisierung der menschlichen Physiologie eingesetzt wird …

Dramatic effect of the specific solvation on the reactivity of quaternary ammonium fluorides and poly (hydrogen fluorides),(HF) n. cntdot. F-, in media of low polarity

D Landini, A Maia, A Rampoldi - The Journal of Organic …, 1989 - ACS Publications
A quantitative study of how the intrinsic reactivity (nucleophilicity and basicity) of the fluoride
anion of hexyl4N+ F" is affected in solvents of low polarity bythe specific solvation of a …

Small prosthetic groups in 18F-radiochemistry: useful auxiliaries for the design of 18F-PET tracers

R Schirrmacher, B Wängler, J Bailey… - Seminars in nuclear …, 2017 - Elsevier
Prosthetic group (PG) applications in 18 F-radiochemistry play a pivotal role among current
18 F-labeling techniques for the development and availability of 18 F-labeled imaging …

PET designated flouride-18 production and chemistry

O Jacobson, X Chen - Current topics in medicinal chemistry, 2010 - ingentaconnect.com
Positron emission tomography (PET) is a nuclear medicine imaging technology which
allows for four-dimensional, quantitative determination of the distribution of labeled …