[HTML][HTML] Sustained proliferation in cancer: Mechanisms and novel therapeutic targets

MA Feitelson, A Arzumanyan, RJ Kulathinal… - Seminars in cancer …, 2015 - Elsevier
Proliferation is an important part of cancer development and progression. This is manifest by
altered expression and/or activity of cell cycle related proteins. Constitutive activation of …

Gallic acid: A potential anti-cancer agent

Y Jiang, J Pei, Y Zheng, Y Miao, B Duan… - Chinese journal of …, 2022 - Springer
Cancer is one of the most devastating diseases worldwide and definitive therapeutics for
treating cancer are not yet available despite extensive research efforts. The key challenges …

Research progress of polycyclic polyprenylated acylphloroglucinols

XW Yang, RB Grossman, G Xu - Chemical reviews, 2018 - ACS Publications
Polycyclic polyprenylated acylphloroglucinols (PPAPs) are a class of hybrid natural products
sharing the mevalonate/methylerythritol phosphate and polyketide biosynthetic pathways …

Non-apoptotic cell death-based cancer therapy: Molecular mechanism, pharmacological modulators, and nanomedicine

X Wang, P Hua, C He, M Chen - Acta Pharmaceutica Sinica B, 2022 - Elsevier
As an emerging cancer therapeutic target, non-apoptotic cell death such as ferroptosis,
necroptosis and pyroptosis, etc., has revealed significant potential in cancer treatment for …

Targeting drug chemo-resistance in cancer using natural products

WH Talib, AR Alsayed, M Barakat, MI Abu-Taha… - Biomedicines, 2021 - mdpi.com
Cancer is one of the leading causes of death globally. The development of drug resistance
is the main contributor to cancer-related mortality. Cancer cells exploit multiple mechanisms …

Autophagy-modulating phytochemicals in cancer therapeutics: Current evidences and future perspectives

S Patra, SR Mishra, BP Behera, KK Mahapatra… - Seminars in cancer …, 2022 - Elsevier
Autophagy is an intracellular catabolic self-cannibalism that eliminates dysfunctional
cytoplasmic cargos by the fusion of cargo-containing autophagosomes with lysosomes to …

Autophagic flux disruption contributes to Ganoderma lucidum polysaccharide-induced apoptosis in human colorectal cancer cells via MAPK/ERK activation

H Pan, Y Wang, K Na, Y Wang, L Wang, Z Li… - Cell death & …, 2019 - nature.com
Targeting autophagy may serve as a promising strategy for cancer therapy. Ganoderma
lucidum polysaccharide (GLP) has been shown to exert promising anti-cancer effects …

New visions on natural products and cancer therapy: autophagy and related regulatory pathways

A Martelli, M Omrani, M Zarghooni, V Citi, S Brogi… - Cancers, 2022 - mdpi.com
Simple Summary In the past few years, clinical as well as regular scientists have been
paying attention to medicinal applications of natural products. There are several …

Targeting programmed cell death using small‐molecule compounds to improve potential cancer therapy

B Ke, M Tian, J Li, B Liu, G He - Medicinal research reviews, 2016 - Wiley Online Library
Evasion of cell death is one of the hallmarks of cancer cells, beginning with long‐
established apoptosis and extending to other new forms of cell death. An elaboration of cell …

[HTML][HTML] Anti-COVID-19 drug candidates: A review on potential biological activities of natural products in the management of new coronavirus infection

A Prasansuklab, A Theerasri, P Rangsinth… - Journal of Traditional …, 2021 - Elsevier
Background and aim The novel coronavirus disease (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is now become a worldwide pandemic …