Mechanisms underlying HIV-associated cognitive impairment and emerging therapies for its management

RJ Ellis, MJ Marquine, M Kaul, JA Fields… - Nature Reviews …, 2023 - nature.com
People living with HIV are affected by the chronic consequences of neurocognitive
impairment (NCI) despite antiretroviral therapies that suppress viral replication, improve …

The role of GPLD1 in chronic diseases

J Cao, A Zhou, Z Zhou, H Liu… - Journal of cellular …, 2023 - Wiley Online Library
Glycosylphosphatidylinositol‐specific phospholipase D (GPLD1) is a specific enzyme for
glycosylphosphatidylinositol (GPI) anchors, thereby exerting its biological functions by …

[HTML][HTML] Exercise promotes angiogenesis by enhancing endothelial cell fatty acid utilization via liver-derived extracellular vesicle miR-122-5p

J Lou, J Wu, M Feng, X Dang, G Wu, H Yang… - Journal of Sport and …, 2022 - Elsevier
Background Angiogenesis constitutes a major mechanism responsible for exercise-induced
beneficial effects. Our previous study identified a cluster of differentially expressed …

DIA-based proteomic analysis of plasma protein profiles in patients with severe acute pancreatitis

H Li, Y Xu, X Zhou, T Jin, Z Wang, Y Sun, H Wang… - Molecules, 2022 - mdpi.com
Acute pancreatitis (AP) is a pancreatic inflammatory disease that varies greatly in course
and severity. To further the understanding of the pathology of AP, we carried out data …

Exercise mimetics: a novel strategy to combat neuroinflammation and Alzheimer's disease

R Zhao - Journal of Neuroinflammation, 2024 - Springer
Neuroinflammation is a pathological hallmark of Alzheimer's disease (AD), characterized by
the stimulation of resident immune cells of the brain and the penetration of peripheral …

Modulation of GPC-4 and GPLD1 serum levels by improving glycemic indices in type 2 diabetes: Resistance training and hawthorn extract intervention

A Heidarianpour, M Keshvari, S Shahidi, M Zarei - Heliyon, 2023 - cell.com
Aims This study was designed to investigate the effects of resistance training (RT) and
hawthorn extract (Ha) on Glypican-4 (GPC-4) and Insulin-regulated …

Proteomics profiling reveals lipid metabolism abnormalities during oogenesis in unexplained recurrent pregnancy loss

K Liu, X Xu, L Sun, H Li, Y Jin, X Ma, B Shen… - Frontiers in …, 2024 - frontiersin.org
Background Unexplained recurrent pregnancy loss (URPL) is a clinical dilemma in
reproductive fields. Its diagnosis is mainly exclusionary after extensive clinical examination …

[HTML][HTML] Exercise, Neuroprotective Exerkines, and Parkinson's Disease: A Narrative Review

AK Mitchell, RR Bliss, FC Church - Biomolecules, 2024 - pmc.ncbi.nlm.nih.gov
Parkinson's disease (PD) is a prevalent neurodegenerative disease in which treatment often
includes an exercise regimen. Exercise is neuroprotective in animal models of PD, and …

Interaction of full-length glycosylphosphatidylinositol-anchored proteins with serum proteins and their translocation to cells in vitro depend on the (pre-) diabetic state …

GA Müller, A Lechner, MH Tschöp, TD Müller - Biomedicines, 2021 - mdpi.com
Glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-APs), which are anchored at the
surface of mammalian cultured and tissue cells through a carboxy-terminal GPI glycolipid …

高磷诱导下肢血管平滑肌细胞成骨分化关键差异表达基因筛选及验证.

倪英群, 杨矛, 杨迪, 郭呈林, 朱文君… - Journal of Jilin …, 2024 - search.ebscohost.com
目的: 采用mRNA 高通量测序技术筛选高磷诱导下肢血管平滑肌细胞(VSMCs)
钙化差异表达基因(DEGs), 分析VSMCs 钙化的关键基因及信号通路. 方法: 将人VSMCs …