Characterization of nanodisc-forming peptides for membrane protein studies

B Krishnarjuna, G Sharma, SC Im, R Auchus… - Journal of Colloid and …, 2024 - Elsevier
Lipid-bilayer nanodiscs provide a stable, native-like membrane environment for the
functional and structural studies of membrane proteins and other membrane-binding …

Enhancing the stability and homogeneity of non-ionic polymer nanodiscs by tuning electrostatic interactions

B Krishnarjuna, J Marte, T Ravula… - Journal of colloid and …, 2023 - Elsevier
The nanodisc technology is increasingly used for structural studies on membrane proteins
and drug delivery. The development of synthetic polymer nanodiscs and the recent …

Polymer-nanodiscs as a novel alignment medium for high-resolution NMR-based structural studies of nucleic acids

B Krishnarjuna, T Ravula, EM Faison, M Tonelli… - Biomolecules, 2022 - mdpi.com
Residual dipolar couplings (RDCs) are increasingly used for high-throughput NMR-based
structural studies and to provide long-range angular constraints to validate and refine …

Uncovering the Optimal Molecular Characteristics of Hydrophobe-Containing Polypeptoids to Induce Liposome or Cell Membrane Fragmentation

T Yu, M Omarova, M Zhang, I Hossain, J Chen… - …, 2023 - ACS Publications
Cellular functions of membrane proteins are strongly coupled to their structures and
aggregation states in the cellular membrane. Molecular agents that can induce the …

[HTML][HTML] Peptoid-based macrodiscs of variable lipid composition for structural studies of membrane proteins by oriented-sample solid-state NMR

AR Galiakhmetov, AA Shah, A Lane, CM Davern… - Journal of Structural …, 2024 - Elsevier
Abstract Solid-state Nuclear Magnetic Resonance (NMR) in combination with magnetically
aligned discoidal lipid mimics allows for studying the conformations of membrane proteins in …