Understanding neuroimmune interactions in disorders of gut–brain interaction: from functional to immune-mediated disorders

T Vanuytsel, P Bercik, G Boeckxstaens - Gut, 2023 - gut.bmj.com
Functional gastrointestinal disorders—recently renamed into disorders of gut–brain
interaction—such as irritable bowel syndrome and functional dyspepsia are highly prevalent …

The impact of acute and chronic stress on gastrointestinal physiology and function: a microbiota–gut–brain axis perspective

SJ Leigh, F Uhlig, L Wilmes… - The Journal of …, 2023 - Wiley Online Library
The physiological consequences of stress often manifest in the gastrointestinal tract.
Traumatic or chronic stress is associated with widespread maladaptive changes throughout …

[HTML][HTML] Irritable bowel syndrome: Epidemiology, overlap disorders, pathophysiology and treatment

KY Huang, FY Wang, M Lv, XX Ma… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Irritable bowel syndrome (IBS) is a common chronic gastrointestinal disease with a
significant impact on patients' quality of life and a high socioeconomic burden. And the …

Toward manipulating serotonin signaling via the microbiota–gut–brain axis

BA Everett, P Tran, A Prindle - Current Opinion in Biotechnology, 2022 - Elsevier
Highlights•Serotonin can interact with bacterial proteins with a range of effects.•Serotonin is
used in signaling between members of the microbiome and host.•Microbiome dysbiosis is …

Small intestinal permeability and metabolomic profiles in feces and plasma associate with clinical response in patients with active psoriatic arthritis participating in a …

MS Kragsnaes, J Miguens Blanco… - ACR open …, 2023 - Wiley Online Library
Objective We investigated intestinal permeability and fecal, plasma, and urine metabolomic
profiles in methotrexate‐treated active psoriatic arthritis (PsA) and how this related to clinical …

Application of metabolomics in irritable bowel syndrome in recent 5 years

Y Gao, P Ding, J Wang, C Zhang, G Ji, T Wu - International …, 2023 - Elsevier
Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal
disorders worldwide, characterized by chronic abdominal pain or discomfort and altered …

Effect of gut microbiome on serotonin metabolism: a personalized treatment approach

K Potter, EJ Gayle, S Deb - Naunyn-Schmiedeberg's Archives of …, 2024 - Springer
Several factors including diet, exercise, and medications influence the makeup of the
resilient but adaptable gut microbiome. Bacteria in the gut have a significant role in the …

“Sentinel or accomplice”: gut microbiota and microglia crosstalk in disorders of gut–brain interaction

H Zheng, C Zhang, J Zhang, L Duan - Protein & Cell, 2023 - academic.oup.com
Abnormal brain–gut interaction is considered the core pathological mechanism behind the
disorders of gut–brain interaction (DGBI), in which the intestinal microbiota plays an …

[HTML][HTML] Recent advances in data-and knowledge-driven approaches to explore primary microbial metabolism

BJ Bartmanski, M Rocha… - Current Opinion in …, 2023 - Elsevier
With the rapid progress in metabolomics and sequencing technologies, more data on the
metabolome of single microbes and their communities become available, revealing the …

Irritable bowel syndrome–controversies in diagnosis and management

K Duncanson, D Tikhe, GM Williams… - Expert Review of …, 2023 - Taylor & Francis
Introduction The irritable bowel syndrome (IBS) is the best-recognized disorder of gut brain
interactions (DGBI). However, it is controversial if the Rome IV criteria iteration for IBS …