Ten putative contributors to the obesity epidemic

EJ McAllister, NV Dhurandhar, SW Keith… - Critical reviews in …, 2009 - Taylor & Francis
The obesity epidemic is a global issue and shows no signs of abating, while the cause of
this epidemic remains unclear. Marketing practices of energy-dense foods and institutionally …

Towards a molecular understanding of adaptive thermogenesis

BB Lowell, BM Spiegelman - Nature, 2000 - nature.com
Obesity results when energy intake exceeds energy expenditure. Naturally occurring genetic
mutations, as well as ablative lesions, have shown that the brain regulates both aspects of …

Indoor thermal environment and human health: A systematic review

G Liu, H Chen, Y Yuan, C Song - Renewable and Sustainable Energy …, 2024 - Elsevier
Indoor thermal environment contributes to the comfort of occupants and even affects their
health and well-being. Recent years have witnessed emerging studies on the connection …

Significance and application of melatonin in the regulation of brown adipose tissue metabolism: relation to human obesity

DX Tan, LC Manchester, L Fuentes‐Broto… - Obesity …, 2011 - Wiley Online Library
A worldwide increase in the incidence of obesity indicates the unsuccessful battle against
this disorder. Obesity and the associated health problems urgently require effective …

Implications of nonshivering thermogenesis for energy balance regulation in humans

WD van Marken Lichtenbelt… - American Journal of …, 2011 - journals.physiology.org
The incidence of the metabolic syndrome has reached epidemic levels in the Western world.
With respect to the energy balance, most attention has been given to reducing energy (food) …

Brown fat activation mediates cold-induced thermogenesis in adult humans in response to a mild decrease in ambient temperature

KY Chen, RJ Brychta, JD Linderman… - The Journal of …, 2013 - academic.oup.com
Context: The contribution of brown adipose tissue (BAT) to the energy balance in humans
exposed to sustainable cold has not been completely established, partially because of …

Healthy excursions outside the thermal comfort zone

W van Marken Lichtenbelt, M Hanssen… - Building Research & …, 2017 - Taylor & Francis
The concepts of comfort and health may be related but are not synonyms. New knowledge
has been gathered regarding metabolic health effects of temperature exposure outside the …

Cold-induced thermogenesis in humans

RJ Brychta, KY Chen - European journal of clinical nutrition, 2017 - nature.com
A basic property of endothermic thermoregulation is the ability to generate heat by
increasing metabolism in response to cold ambient temperatures to maintain a stable core …

Brown adipose tissue uncoupling protein content in human infants, children and adults.

ME Lean, WP James, G Jennings… - … (London, England: 1979 …, 1986 - europepmc.org
A solid-phase radioimmunoassay is described for the estimation of the uncoupling protein
content of human brown adipose tissue mitochondria, as an index of thermogenic capacity …

Three years with adult human brown adipose tissue

J Nedergaard, T Bengtsson… - Annals of the New York …, 2010 - Wiley Online Library
The presence of active brown adipose tissue in adult humans has been recognized in
general physiology only since 2007. The intervening three years established that the depots …