Synthesis of Cyclobutanes and Cyclobutenes by Strain-Release-Driven Ring-Opening of Bicyclo [1.1. 0] butanes
X Zhan, HX He, Q Peng, JJ Feng - Synthesis, 2024 - thieme-connect.com
Cyclobutanes and cyclobutenes exhibit intriguing structures and demonstrate significant
biological activities and diverse synthetic applications. This review aims to summarize recent …
biological activities and diverse synthetic applications. This review aims to summarize recent …
Organometallic Bridge Diversification of Bicyclo [1.1. 1] pentanes
JM Anderson, DL Poole, GC Cook… - … A European Journal, 2024 - Wiley Online Library
Abstract Bicyclo [1.1. 1] pentane (BCP) derivatives have attracted significant recent interest
in drug discovery as alkyne, tert‐butyl and arene bioisosteres, where their incorporation is …
in drug discovery as alkyne, tert‐butyl and arene bioisosteres, where their incorporation is …
Synthesis of Stereodefined Polysubstituted Bicyclo [1.1. 0] butanes
R Suresh, N Orbach, I Marek - Journal of the American Chemical …, 2024 - ACS Publications
We report a highly diastereoselective synthesis of polysubstituted bicyclobutanes
possessing up to three stereodefined quaternary centers and five substituents. Our strategy …
possessing up to three stereodefined quaternary centers and five substituents. Our strategy …
Decarboxylative C–N Coupling of 2,2-Difluorobicyclo[1.1.1]pentane (BCP-F2) Building Blocks
X Ma, JL Chen, BE Gaskins - Organic Letters, 2024 - ACS Publications
Described herein is our effort toward achieving the decarboxylative functionalization of 2, 2-
difluorobicyclo [1.1. 1] pentane (BCP-F2) building blocks. When compared with the …
difluorobicyclo [1.1. 1] pentane (BCP-F2) building blocks. When compared with the …
[PDF][PDF] Gabriel Synthesis of Aminomethyl-Bicyclo [1.1. 0] butanes
M Pitchai, KC Nanjundaswamy, S Ulaganathan… - 2024 - chemrxiv.org
Gabriel Synthesis of Aminomethyl-Bicyclo[1.1.0]butanes Page 1 Gabriel Synthesis of
Aminomethyl-Bicyclo[1.1.0]butanes Manivel Pitchai1*, Nanjundaswamy KC1, Sankar …
Aminomethyl-Bicyclo[1.1.0]butanes Manivel Pitchai1*, Nanjundaswamy KC1, Sankar …
[PDF][PDF] Gabriel Synthesis of Aminomethyl-Bicyclo [1.1. 0] butanes Manivel Pitchai1*, Nanjundaswamy KC, Sankar Ulaganathan1, Mohammad Javeed1, Pavan …
M Pitchai - chemrxiv.org
General Experimental. All solvents were purchased from Sigma-Aldrich and used without
further purification. All reactions involving heating were performed in aluminum heating …
further purification. All reactions involving heating were performed in aluminum heating …