Mechanisms, challenges and opportunities in stroke

EH Lo, T Dalkara, MA Moskowitz - Nature reviews neuroscience, 2003 - nature.com
Over the past two decades, research has heavily emphasized basic mechanisms that
irreversibly damage brain cells after stroke. Much attention has focused on what makes …

Therapeutic hypothermia after cardiac arrest: an advisory statement by the advanced life support task force of the International Liaison Committee on Resuscitation

Writing Group, JP Nolan, PT Morley, TL Vanden Hoek… - Circulation, 2003 - Am Heart Assoc
● Unconscious adult patients with spontaneous circulation after out-of-hospital cardiac
arrest should be cooled to 32 C to 34 C for 12 to 24 hours when the initial rhythm was …

Neuroprotection for ischemic stroke: past, present and future

MD Ginsberg - Neuropharmacology, 2008 - Elsevier
Neuroprotection for ischemic stroke refers to strategies, applied singly or in combination, that
antagonize the injurious biochemical and molecular events that eventuate in irreversible …

European Resuscitation Council guidelines for resuscitation 2005: Section 4. Adult advanced life support

JP Nolan, CD Deakin, J Soar, BW Böttiger… - …, 2005 - resuscitationjournal.com
European Resuscitation Council Guidelines for Resuscitation 2005 - Resuscitation Skip to Main
Content Skip to Main Menu Advertisement Resuscitation European Resuscitation Council …

Temperature management after cardiac arrest: an advisory statement by the advanced life support task force of the international liaison committee on resuscitation and …

MW Donnino, LW Andersen, KM Berg, JC Reynolds… - Circulation, 2015 - Am Heart Assoc
For more than a decade, mild induced hypothermia (32° C–34° C) has been standard of
care for patients remaining comatose after resuscitation from out-of-hospital cardiac arrest …

Effects of hypothermia on energy metabolism in Mammalian central nervous system

M Erecinska, M Thoresen… - Journal of Cerebral Blood …, 2003 - journals.sagepub.com
This review analyzes, in some depth, results of studies on the effect of lowered temperatures
on cerebral energy metabolism in animals under normal conditions and in some selected …

European Resuscitation Council Guidelines for Resuscitation 2005: Section 2. Adult basic life support and use of automated external defibrillators

AJ Handley, R Koster, K Monsieurs, GD Perkins… - Resuscitation, 2005 - Elsevier
Basic life support (BLS) refers to maintaining airway patency and supporting breathing and
the circulation, without the use of equipment other than a protective device. 1 T his section …

Thermoregulation: physiological and clinical considerations during sedation and general anesthesia

M Díaz, DE Becker - Anesthesia progress, 2010 - meridian.allenpress.com
Mild hypothermia is common during deep sedation or general anesthesia and is frequently
associated with patient discomfort and shivering. Greater declines in temperature can …

Selective head cooling in newborn infants after perinatal asphyxia: a safety study

AJ Gunn, PD Gluckman, TR Gunn - Pediatrics, 1998 - publications.aap.org
Aims. To determine the practicality and safety of head cooling with mild or minimal systemic
hypothermia in term neonates with moderate to severe hypoxic-ischemic encephalopathy …

Perinatal brain injury in the preterm and term newborn

AJ du Plessis, JJ Volpe - Current opinion in neurology, 2002 - journals.lww.com
Major advances in understanding the cellular mechanisms of brain injury have presented a
host of potential targets for intervention. This is particularly true of hypoxic-ischemic injury …