APT‐weighted MRI: techniques, current neuro applications, and challenging issues

J Zhou, HY Heo, L Knutsson… - Journal of Magnetic …, 2019 - Wiley Online Library
Amide proton transfer‐weighted (APTw) imaging is a molecular MRI technique that
generates image contrast based predominantly on the amide protons in mobile cellular …

Magnetization transfer contrast and chemical exchange saturation transfer MRI. Features and analysis of the field-dependent saturation spectrum

PCM Van Zijl, WW Lam, J Xu, L Knutsson, GJ Stanisz - Neuroimage, 2018 - Elsevier
Abstract Magnetization Transfer Contrast (MTC) and Chemical Exchange Saturation
Transfer (CEST) experiments measure the transfer of magnetization from molecular protons …

Clinical applications of chemical exchange saturation transfer (CEST) MRI

KM Jones, AC Pollard, MD Pagel - Journal of Magnetic …, 2018 - Wiley Online Library
Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) has
been developed and employed in multiple clinical imaging research centers worldwide …

Chemical exchange saturation transfer (CEST) and MR Z-spectroscopy in vivo: a review of theoretical approaches and methods

M Zaiss, P Bachert - Physics in Medicine & Biology, 2013 - iopscience.iop.org
Chemical exchange saturation transfer (CEST) of metabolite protons that undergo exchange
processes with the abundant water pool enables a specific contrast for magnetic resonance …

Assessing the predictability of IDH mutation and MGMT methylation status in glioma patients using relaxation-compensated multipool CEST MRI at 7.0 T

D Paech, J Windschuh, J Oberhollenzer… - Neuro …, 2018 - academic.oup.com
Background Early identification of prognostic superior characteristics in glioma patients such
as isocitrate dehydrogenase (IDH) mutation and O6-methylguanine-DNA-methyltransferase …

The relayed nuclear Overhauser effect in magnetization transfer and chemical exchange saturation transfer MRI

Y Zhou, C Bie, PCM van Zijl, NN Yadav - NMR in biomedicine, 2023 - Wiley Online Library
Magnetic resonance (MR) is a powerful technique for noninvasively probing molecular
species in vivo but suffers from low signal sensitivity. Saturation transfer (ST) MRI …

Downfield‐NOE‐suppressed amide‐CEST‐MRI at 7 Tesla provides a unique contrast in human glioblastoma

M Zaiss, J Windschuh, S Goerke… - Magnetic resonance …, 2017 - Wiley Online Library
Purpose The chemical exchange saturation transfer (CEST) effect observed in brain tissue
in vivo at the frequency offset 3.5 ppm downfield of water was assigned to amide protons of …

Snapshot‐CEST: optimizing spiral‐centric‐reordered gradient echo acquisition for fast and robust 3D CEST MRI at 9.4 T

M Zaiss, P Ehses, K Scheffler - NMR in Biomedicine, 2018 - Wiley Online Library
Gradient echo (GRE)‐based acquisition provides a robust readout method for chemical
exchange saturation transfer (CEST) at ultrahigh field (UHF). To develop a snapshot‐CEST …

Theory of chemical exchange saturation transfer MRI in the context of different magnetic fields

M Zaiss, T Jin, SG Kim, DF Gochberg - NMR in Biomedicine, 2022 - Wiley Online Library
Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) is a
versatile MRI method that provides contrast based on the level of molecular and metabolic …

Creatine and phosphocreatine mapping of mouse skeletal muscle by a polynomial and Lorentzian line‐shape fitting CEST method

L Chen, PB Barker, RG Weiss… - Magnetic resonance …, 2019 - Wiley Online Library
Purpose To obtain high‐resolution Cr and PCr maps of mouse skeletal muscle using a
polynomial and Lorentzian line‐shape fitting (PLOF) CEST method. Methods Wild‐type mice …