Migraine is two to three times more prevalent in women than men, and women report a
longer attack duration, increased risk of headache recurrence, greater disability, and a …

The study aims to provide an updated assessment of the evidence for individual
pharmacological therapies for acute migraine treatment. Pharmacological therapy is …

Objective To evaluate the efficacy and safety of eptinezumab, a humanized anti-calcitonin
gene-related peptide monoclonal antibody, in the preventive treatment of episodic migraine …

Importance Migraine is the second leading cause of disability worldwide. Most patients with
migraine discontinue medications due to inefficacy or adverse effects. Mindfulness-based …

Objective To assess the efficacy and safety of lasmiditan in the acute treatment of migraine.
Methods Adult patients with migraine were randomized (1: 1: 1) to a double-blind dose of …

Clinical trials are a key component of the evidence base for the treatment of headache
disorders. In 1991, the International Headache Society Clinical Trials Standing Committee …

Importance The long-term prophylactic effects of acupuncture for migraine are uncertain.
Objective To investigate the long-term effects of true acupuncture compared with sham …

Background Which medication, if any, to use to prevent the headache of pediatric migraine
has not been established. Methods We conducted a randomized, double-blind, placebo …

Background Several drugs are available for the preventive treatment of both episodic and
chronic migraine. The choice of which therapy to initiate first, second, or third is not …

The quality of clinical trials is an essential part of the evidence base for the treatment of
headache disorders. In 1991, the International Headache Society Clinical Trials Standing …