Quantification of liver fat content with CT and MRI: state of the art

J Starekova, D Hernando, PJ Pickhardt, SB Reeder - Radiology, 2021 - pubs.rsna.org
Hepatic steatosis is defined as pathologically elevated liver fat content and has many
underlying causes. Nonalcoholic fatty liver disease (NAFLD) is the most common chronic …

Noninvasive assessment of liver disease in patients with nonalcoholic fatty liver disease

L Castera, M Friedrich-Rust, R Loomba - Gastroenterology, 2019 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is estimated to afflict approximately 1 billion
individuals worldwide. In a subset of NAFLD patients, who have the progressive form of …

Linearity, bias, and precision of hepatic proton density fat fraction measurements by using MR imaging: a meta-analysis

T Yokoo, SD Serai, A Pirasteh, MR Bashir, G Hamilton… - Radiology, 2018 - pubs.rsna.org
Purpose To determine the linearity, bias, and precision of hepatic proton density fat fraction
(PDFF) measurements by using magnetic resonance (MR) imaging across different field …

Liver fat imaging—a clinical overview of ultrasound, CT, and MR imaging

YN Zhang, KJ Fowler, G Hamilton, JY Cui… - The British journal of …, 2018 - academic.oup.com
Hepatic steatosis is a frequently encountered imaging finding that may indicate chronic liver
disease, the most common of which is non-alcoholic fatty liver disease. Non-alcoholic fatty …

Microbiome signatures associated with steatohepatitis and moderate to severe fibrosis in children with nonalcoholic fatty liver disease

JB Schwimmer, JS Johnson, JE Angeles, C Behling… - Gastroenterology, 2019 - Elsevier
Background & Aims The intestinal microbiome might affect the development and severity of
nonalcoholic fatty liver disease (NAFLD). We analyzed microbiomes of children with and …

[PDF][PDF] Magnetic resonance elastography predicts advanced fibrosis in patients with nonalcoholic fatty liver disease: a prospective study

R Loomba, T Wolfson, B Ang, J Hooker, C Behling… - …, 2014 - Wiley Online Library
Retrospective studies have shown that two‐dimensional magnetic resonance elastography
(2D‐MRE), a novel MR method for assessment of liver stiffness, correlates with advanced …

[HTML][HTML] Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans

S Timmers, E Konings, L Bilet, RH Houtkooper… - Cell metabolism, 2011 - cell.com
Resveratrol is a natural compound that affects energy metabolism and mitochondrial
function and serves as a calorie restriction mimetic, at least in animal models of obesity …

[HTML][HTML] Radiologic evaluation of nonalcoholic fatty liver disease

SS Lee, SH Park - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is a frequent cause of chronic liver diseases,
ranging from simple steatosis to nonalcoholic steatohepatitis (NASH)-related liver cirrhosis …

Quantitative assessment of liver fat with magnetic resonance imaging and spectroscopy

SB Reeder, I Cruite, G Hamilton… - Journal of magnetic …, 2011 - Wiley Online Library
Hepatic steatosis is characterized by abnormal and excessive accumulation of lipids within
hepatocytes. It is an important feature of diffuse liver disease, and the histological hallmark …

[PDF][PDF] Utility of magnetic resonance imaging versus histology for quantifying changes in liver fat in nonalcoholic fatty liver disease trials

M Noureddin, J Lam, MR Peterson, M Middleton… - …, 2013 - Wiley Online Library
The magnetic resonance imaging–estimated proton density fat fraction (MRI‐PDFF) is a
novel imaging‐based biomarker that allows fat mapping of the entire liver, whereas the …