Leukemic transformation in myeloproliferative neoplasms (MPN), also referred to as “blast-
phase MPN”, is the most feared disease complication, with incidence estimates of 1–4% for …

Current Treatment Options in Oncology and how they modulate FLT3I's activity is important
to rationalize combinational treatment approaches including FLT3Is and modulators of …

A total of 14 consecutive I IDH1/2 i-mutated patients with MPN-BP (median age 76 years)
received ivosidenib (I ni= 5) or enasidenib (I ni= 9), either in the up-front (I ni= 8) or relapsed …

The mainstay of acute myeloid leukemia (AML) treatment still relies on traditional
chemotherapy, with a survival rate of approximately 30% for patients under 65 years of age …

Regulated cell death (RCD) plays a crucial role in the initiation and progression of tumors,
particularly in acute myeloid leukemia (AML). This study investigates the prognostic …

The myeloproliferative neoplasms (MPNs) are a group of acquired clonal disorders where
mutations drive proliferative disease resulting in increased blood counts and in some cases …

Hematologic malignancies are the most common hematopoietic diseases and a major
public health concern. However, the mechanisms underlying myeloid tumors remain …

The discovery of cancer-specific biomarkers has resulted in major advancements in the field
of cancer diagnostics and therapeutics, therefore significantly lowering cancer-related …

Acute myeloid leukemia is one of the deadliest hematologic malignancies that is marked by
genetic alterations, abnormal cellular functions and proliferation. Mutations in isocitrate …

RESUME L'inceste et sa prohibition apparaissent comme des notions complexes qui ne
supportent de définition qu'à travers les différents champs qui l'ont étudié. L'inceste …