Therapies directed toward the central nervous system remain difficult to translate into
improved clinical outcomes. This is largely due to the blood–brain barrier (BBB), arguably …

Self-assembled peptide and protein amyloid nanostructures have traditionally been
considered only as pathological aggregates implicated in human neurodegenerative …

Nanoparticles are generally defined as any particulate material for which at least one
dimension lies in the range of 1− 100 nm. 1− 3 They can exist in various shapes, such as …

Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …

This review is concerned with the role of fibrillization of the amyloid β (Aβ)-peptide in
Alzheimer's disease (AD). The perspective is that of a physical chemist, and one aim is to …

1.1. Historic Perspective Silica and doped silica materials obtained via the solution− gelation
(“sol− gel”) inorganic polymerization process are functional materials with an impressive …

Nanomedicine, the use of nanotechnology for biomedical applications, has potential to
change the landscape of the diagnosis and therapy of many diseases. In the past several …

Silica is one of the most abundant minerals in the Earth's crust, and over time it has been
introduced first into human life and later into engineering. Silica is present in the food chain …

Background Fluorescent silica nanoparticles have been extensively utilised in a broad
range of biological applications and are facilitated by their predictable, well-understood …

Chronic wounds are not only a burden for patients but also challenging for clinic treatment
due to biofilm formation. Here, we utilized the phenomenon that chronic wounds possess an …