Iron and manganese-related CNS toxicity: mechanisms, diagnosis and treatment

P Chen, M Totten, Z Zhang, H Bucinca… - Expert review of …, 2019 - Taylor & Francis
ABSTRACT Introduction: Iron (Fe) and manganese (Mn) are essential nutrients for humans.
They act as cofactors for a variety of enzymes. In the central nervous system (CNS), these …

Manganese exposure and neurologic outcomes in adult populations

KV Martin, D Edmondson, KM Cecil… - Neurologic …, 2020 - neurologic.theclinics.com
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[HTML][HTML] Whole-brain mapping of increased manganese levels in welders and its association with exposure and motor function

H Monsivais, CL Yeh, A Edmondson, R Harold… - NeuroImage, 2024 - Elsevier
Although manganese (Mn) is a trace metal essential for humans, chronic exposure to Mn
can cause accumulation of this metal ion in the brain leading to an increased risk of …

[HTML][HTML] Serum biomarkers of liver fibrosis identify globus pallidus vulnerability

AJ Kwong, NM Zahr - NeuroImage: Clinical, 2023 - Elsevier
The CNS manifestation of chronic liver disease can include magnetic resonance (MR) signal
hyperintensities in basal ganglia structures. Here, relations between liver (serum-derived …

Manganese exposure and working memory-related brain activity in smallholder farmworkers in Costa Rica: Results from a pilot study

VA Palzes, SK Sagiv, JM Baker, D Rojas-Valverde… - Environmental …, 2019 - Elsevier
Main sources of manganese (Mn) in the general population are diet and drinking water. Mn
is also found in ethylene bisdithiocarbamate (EBDC) fungicides used in agriculture or …

Manganese induced nervous injury by α-synuclein accumulation via ATP-sensitive K (+) channels and GABA receptors

Y Sun, Y He, L Yang, D Liang, W Shi, X Zhu, Y Jiang… - Toxicology Letters, 2020 - Elsevier
Manganese (Mn) is an environmental pollutant having a toxic effect on Parkinson's disease,
with significant damage seen in the neurons of basal ganglia. Hence, Mn pollution is a …

The association of bone, fingernail and blood manganese with cognitive and olfactory function in Chinese workers

D Rolle-McFarland, Y Liu, F Mostafaei… - Science of the Total …, 2019 - Elsevier
Occupational manganese (Mn) exposure has been associated with cognitive and olfactory
dysfunction; however, few studies have incorporated cumulative biomarkers of Mn exposure …

Effects of mixed metal exposure on MRI metrics in basal ganglia

J Kim, BG Kim, YS Hong, EY Lee - Toxicological Sciences, 2024 - academic.oup.com
Welding fumes contain various metals. Past studies, however, mainly focused on
Manganese (Mn)-related neurotoxicity. This study investigated welding-related mixed metal …

[HTML][HTML] Welding techniques and manganese concentrations in blood and brain: Results from the WELDFUMES study

P Thunberg, G Wastensson, G Lidén, M Adjeiwaah… - Neurotoxicology, 2024 - Elsevier
This study used whole-brain mapping to investigate the effect of different welding processes
on manganese (Mn) accumulation in the brain. Exposure measurements were performed at …

Magnetic Resonance Imaging and Manganism: A Narrative Review and Laboratory Recommendations

M Majewski, K Piwko, M Ordak, E Muszynska… - Journal of Clinical …, 2024 - mdpi.com
In recent years, a series of articles has been published concerning magnetic resonance
imaging (MRI) studies in a group of patients exposed to manganism, specifically factory …